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ChemicalBook CAS DataBase List 2,4-Dibromo-16a-hydroxyestrone
79258-14-3

2,4-Dibromo-16a-hydroxyestrone synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 85 percent / CuBr2 / methanol / 48 h / Heating
2: 97 percent / NaOH, 75percent aq. pyridine / 3 h / Ambient temperature

References:

Numazawa, Mitsuteru;Nagaoka, Masao;Tsuji, Masachika;Osawa, Yoshio [Journal of the Chemical Society. Chemical communications,1981,# 8,p. 383 - 384]