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ChemicalBook CAS DataBase List 2,4-BIS(BENZYLOXY)PYRIMIDINE-5-BORONIC ACID
70523-24-9

2,4-BIS(BENZYLOXY)PYRIMIDINE-5-BORONIC ACID synthesis

1synthesis methods
-

Yield: 95%

Reaction Conditions:

Stage #1:5-bromo-2,4-bis(benzyloxy)pyrimidine with n-butyllithium;Triisopropyl borate in tetrahydrofuran;hexane;toluene at 20; for 18 h;
Stage #2: with hydrogenchloride in tetrahydrofuran;hexane;toluene

References:

Seley, Katherine L.;Salim, Samer;Zhang, Liang;O'Daniel, Peter I. [Journal of Organic Chemistry,2005,vol. 70,# 5,p. 1612 - 1619]

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