2,3-Dichlorotoluene synthesis
- Product Name:2,3-Dichlorotoluene
- CAS Number:32768-54-0
- Molecular formula:C7H6Cl2
- Molecular Weight:161.03
608-26-4
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$165.00/500mg
1333-74-0
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$190.00/56L
32768-54-0
257 suppliers
$9.00/25g
Yield:32768-54-0 92%
Reaction Conditions:
with chlorine;triphenylphosphine in chlorobenzene
Steps:
1 EXAMPLE 1
EXAMPLE 1 Over a period of 3 hours, 239 g of chlorine were passed into a mixture of 880 g of triphenylphosphine and 1000 ml of chlorobenzene while stirring vigorously, with the temperature being 40° C. for the first 2 hours, then 50° C. A solution of 456 g of 2-chloro-3-methyl-phenol in 200 ml of chlorobenzene was allowed to run dropwise into the mixture obtained above at 40° C. over the course of 90 minutes. At atmospheric pressure, the temperature of the reaction mixture was subsequently gradually increased to 150° C., with vigorous evolution of gaseous hydrogen chloride commencing when 80° C. was reached. During the reaction and subsequent thereto, a total of 1314 g of hydrogen chloride-containing chlorobenzene was collected as distillate until a bottom temperature of 150° C. was reached. The residue was subjected to a distillation at from 5 to 10 mbar. This gave 2,3-dichlorotoluene in a yield of 92% of theory.
References:
Bayer Aktiengesellschaft US5648570, 1997, A
95-49-8
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$10.00/5g
19398-61-9
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$10.00/5 g
118-69-4
290 suppliers
$14.00/5g
95-73-8
255 suppliers
$14.00/5g
32768-54-0
257 suppliers
$9.00/25g
29027-17-6
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$15.00/100mg
32768-54-0
257 suppliers
$9.00/25g
108-88-3
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$21.80/5 mL
32768-54-0
257 suppliers
$9.00/25g