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ChemicalBook CAS DataBase List tert-Butyl 4-(4-amino-2-fluorophenyl)piperidine-1-carboxylate
188975-15-7

tert-Butyl 4-(4-amino-2-fluorophenyl)piperidine-1-carboxylate synthesis

3synthesis methods
1(2H)-Pyridinecarboxylic acid, 4-(2-fluoro-4-nitrophenyl)-3,6-dihydro-, 1,1-dimethylethyl ester

1373420-25-7
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tert-Butyl 4-(4-amino-2-fluorophenyl)piperidine-1-carboxylate

188975-15-7
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Yield:188975-15-7 96%

Reaction Conditions:

with 10% Pd/C;hydrogen in ethyl acetate at 30; for 16 h;

References:

WO2014/26242,2014,A1 Location in patent:Page/Page column 98; 99

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