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ChemicalBook CAS DataBase List (1R,2R,3S,5R)-3-Amino-2,6,6-trimethylbicyclo[3.1.1]heptan-2-ol
168286-10-0

(1R,2R,3S,5R)-3-Amino-2,6,6-trimethylbicyclo[3.1.1]heptan-2-ol synthesis

2synthesis methods
Bicyclo[3.1.1]heptan-3-one, 2-hydroxy-2,6,6-trimethyl-, oxime, (1R,2R,5R)-

126061-28-7
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(1R,2R,3S,5R)-3-Amino-2,6,6-trimethylbicyclo[3.1.1]heptan-2-ol

168286-10-0
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Yield:168286-10-0 80%

Reaction Conditions:

with lithium aluminium tetrahydride in tetrahydrofuran at 0;Reflux;

References:

Frensch, Gustavo;Labes, Ricardo;Wosch, Celso Luiz;Munaretto, Laieli Dos Santos;Salomé, Kahlil Schwanka;Guerrero, Palimécio G.;Marques, Francisco A. [Tetrahedron Letters,2016,vol. 57,# 3,p. 420 - 422] Location in patent:supporting information

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