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(7a,17b)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)thio]nonyl]-estra-1,3,5(10)-triene-3,17-diol synthesis
- Product Name:(7a,17b)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)thio]nonyl]-estra-1,3,5(10)-triene-3,17-diol
- CAS Number:153004-31-0
- Molecular formula:C32H47F5O2S
- Molecular Weight:590.77
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862700-70-7
15 suppliers
$675.00/5mg
![(7a,17b)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)thio]nonyl]-estra-1,3,5(10)-triene-3,17-diol](/CAS2/GIF/153004-31-0.gif)
153004-31-0
106 suppliers
$498.06/5MG
Yield:153004-31-0 81%
Reaction Conditions:
with triethylsilane;boron trifluoride diethyl etherate in dichloromethane at 0; for 14 h;
Steps:
Synthesis of Compound 7; To a solution of compound 6 (8.8g, 11.38 mmol) in dichloromethane (440 mL) was added Et3SiH (88 mL). The reaction was cooled to 0 0C. BF3 Et2O (176 mL) was added dropwise. After the addition was complete (-14 h). The mixture was extracted with ethyl acetate (250 ml, 200 ml and 150 ml). The combined extract was washed with saturated brine(200 ml x 2) and dried over Na2SO4. Solvent was evaporated to give a crude product. The
References:
WO2009/39700,2009,A1 Location in patent:Page/Page column 6-7
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129453-61-8
472 suppliers
$28.00/1mg
![(7a,17b)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)thio]nonyl]-estra-1,3,5(10)-triene-3,17-diol](/CAS2/GIF/153004-31-0.gif)
153004-31-0
106 suppliers
$498.06/5MG
![Estra-1,3,5(10)-triene-3,17-diol,7-[9-[(4,4,5,5,5-pentafluoropentyl)thio]nonyl]-,17-acetate,(7a,17b)-](/CAS2/GIF/875573-69-6.gif)
875573-69-6
134 suppliers
inquiry
![(7a,17b)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)thio]nonyl]-estra-1,3,5(10)-triene-3,17-diol](/CAS2/GIF/153004-31-0.gif)
153004-31-0
106 suppliers
$498.06/5MG

148043-73-6
287 suppliers
$15.00/2g
![(7a,17b)-7-[9-[(4,4,5,5,5-Pentafluoropentyl)thio]nonyl]-estra-1,3,5(10)-triene-3,17-diol](/CAS2/GIF/153004-31-0.gif)
153004-31-0
106 suppliers
$498.06/5MG