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ChemicalBook CAS DataBase List tert-butyl N-[3-[methoxy(methyl)amino]-3-oxopropyl]carbamate
142570-56-7

tert-butyl N-[3-[methoxy(methyl)amino]-3-oxopropyl]carbamate synthesis

8synthesis methods
3303-84-2 Synthesis
Boc-beta-alanine

3303-84-2
373 suppliers
$6.00/5g

6638-79-5 Synthesis
N,O-Dimethylhydroxylamine hydrochloride

6638-79-5
573 suppliers
$6.00/25g

-

Yield:142570-56-7 100%

Reaction Conditions:

Stage #1: N-tert-butoxycarbonyl-β-alaninewith 4-methyl-morpholine;isobutyl chloroformate in dichloromethane at -15; for 0.25 h;
Stage #2: O,N-dimethyl-hydroxylamine hydrochloride in dichloromethane at -15 - 20; for 16 h;

References:

Blaney, Paul;Grigg, Ronald;Rankovic, Zoran;Thornton-Pett, Mark;Xu, Juan [Tetrahedron,2002,vol. 58,# 9,p. 1719 - 1737]

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