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13972-97-9

3-Isoquinolinecarboxylic acid, 1,2-dihydro-4-hydroxy-1-oxo-, Methyl ester synthesis

1synthesis methods
-

Yield:13972-97-9 91%

Reaction Conditions:

with sodium methylate in methanol for 24 h;Reflux;Gabriel-Coleman rearrangement (Gabriel isoquinoline synthesis);

References:

Kapatsina, Elisabeth;Lordon, Marie;Baro, Angelika;Laschat, Sabine [Synthesis,2008,# 16,art. no. Z09208SS,p. 2551 - 2560] Location in patent:body text

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