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1334330-32-3

2-benzyl-2-aza-bicyclo[3.1.1]heptane-1-carboxylic acid hydrochloride synthesis

5synthesis methods
1169708-27-3 Synthesis
2-(Phenylmethyl)-2-azabicyclo-[3.1.1]heptane-1-carbonitrile

1169708-27-3
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2-benzyl-2-aza-bicyclo[3.1.1]heptane-1-carboxylic acid hydrochloride

1334330-32-3
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Yield:1334330-32-3 98%

Reaction Conditions:

with hydrogenchloride;waterReflux;Inert atmosphere;

References:

De Blieck, Ann;Stevens, Christian V. [Synlett,2011,# 12,p. 1748 - 1752] Location in patent:supporting information; experimental part