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ChemicalBook CAS DataBase List 5-[(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)METHYL]-2-FURALDEHYDE
116750-06-2

5-[(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)METHYL]-2-FURALDEHYDE synthesis

3synthesis methods
-

Yield:116750-06-2 89.5%

Reaction Conditions:

in N,N-dimethyl-formamide at 80; for 3 h;Gabriel Amine Synthesis;Temperature;

Steps:

1.1; 2.1; 3.1; 4.1 (1) Gabriel reaction

Put 102mg of 5-CMF, 185mg of KPI, and 20mL of DMF in a round-bottomed flask and mix well. At 80 ° C, react for 3 hours. After the reaction, filter and collect the filtrate. Add 4 ° C deionized water to the filtrate and let stand. After 30 min, filtering and collecting solids, the 5-PMF yield was determined to be 89.5%.

References:

CN110330440,2019,A Location in patent:Paragraph 0025; 0027-0028; 0036-0038; 0045-0047; 0054-0056