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ChemicalBook CAS DataBase List 2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide hydrochloride
1038915-56-8

2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide hydrochloride synthesis

1synthesis methods
tert-butyl 3-(4-(7-carbamoyl-2H-indazol-2-yl)phenyl)piperidine-1-carboxylate

1038915-92-2
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2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide hydrochloride

1038915-56-8
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Yield:1038915-56-8 93%

Reaction Conditions:

with hydrogenchloride in water;ethyl acetate at 20; for 3 h;

References:

Jones, Philip;Altamura, Sergio;Boueres, Julia;Ferrigno, Federica;Fonsi, Massimiliano;Giomini, Claudia;Lamartina, Stefania;Monteagudo, Edith;Ontoria, Jesus M.;Orsale, Maria Vittoria;Palumbi, Maria Cecilia;Pesci, Silvia;Roscilli, Giuseppe;Scarpelli, Rita;Schultz-Fademrecht, Carsten;Toniatti, Carlo;Rowley, Michael [Journal of Medicinal Chemistry,2009,vol. 52,# 22,p. 7170 - 7185] Location in patent:experimental part