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10021-79-1

1-[1-(3-chlorophenyl)-5-methyl-1H-pyrazol-4-yl]ethan-1-one synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: 71 percent / sodium ethoxide / ethanol; diethyl ether / 15 h / Ambient temperature
2: 80 percent / 10percent aq. sodium hydroxide / ethanol / 2 h / Heating
3: 55 percent / Heating

References:

Bernard;Cocco;Maccioni;Plumitallo [Farmaco, Edizione Scientifica,1985,vol. 40,# 4,p. 259 - 271]