1-Triphenylmethyl-4-methylimidazole synthesis
- Product Name:1-Triphenylmethyl-4-methylimidazole
- CAS Number:82594-80-7
- Molecular formula:C23H20N2
- Molecular Weight:324.42
Yield:82594-80-7 98.2%
Reaction Conditions:
with triethylamine in N,N-dimethyl-formamide; for 3.5 h;
Steps:
1 equivalent (i.e. 36.53 mmol, 1 eq.) of 4-methyl-1H-imidazole (1) was dissolved in 120 mL of dimethylformamide, triethylamine (73.06 mmol, 2 eq.) and chlorotriphenylmethane (40.1 mmol, 1.1 eq) where added. The mixture was stirred for 3.5 h. The precipitate filtered off and was washed by means of ice-cooled dimethylformamide (2*50 mL) and water (2*50 mL). After removal of the solvent the remaining product was dried over P4O10. Yield: 10.65 g (98.2%). The product was used without further purification.
References:
US2008/260688,2008,A1 Location in patent:Page/Page column 37