ChemicalBook CAS DataBase List 1-Cyclohexene-1-acetonitrile

1-Cyclohexene-1-acetonitrile synthesis

9synthesis methods

Product Name:1-Cyclohexene-1-acetonitrile
CAS Number:6975-71-9
Molecular formula:C8H11N
Molecular Weight:121.18

7-Oxabicyclo[4.1.0]heptane-1-acetonitrile

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6975-71-9
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Yield: 85%

Reaction Conditions:

with sodium iodide;tin(ll) chloride in ethanol for 0.05 h;Reflux;Green chemistry;

Steps:

General procedure for De oxygenation of aliphatic and aromatic epoxide, chalcone epoxide, nitro styrene epoxide and nitrochromene epoxide by novel SnCl 2 / NaI reagent:
General procedure: To a solution epoxide (1mmol) and NaI (3mmol) in absolute alcohol (5ml), SnCl2 (2mmol) was added in a several portions. The mixture was stirred at reflux temperature and the progress of reaction was monitored by TLC. Within 2-10 min the reaction mixture is poured in ice-water, precipitation obtained, stirred for 10 min and filtered the solid, dried to obtained pure products 2a-12a/ 1b-17b/1c-10c and 1d- 10d with 85-96% yield.

References:

Pathe, Gulab Khushalrao;Ahmed, Naseem [Synthesis,2015,vol. 47,# 22,art. no. SS-2015-Z0312-OP,p. 3542 - 3552]

3399-73-3 Synthesis