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ChemicalBook CAS DataBase List 1-BROMO-4-CHLOROISOQUINOLINE
925890-48-8

1-BROMO-4-CHLOROISOQUINOLINE synthesis

1synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 14 h / 0 - 20 °C
2.1: tetrabutylammomium bromide / dichloromethane / 0.17 h / 20 °C / Inert atmosphere; Molecular sieve
2.2: 20 °C / Inert atmosphere

References:

Wengryniuk, Sarah E.;Weickgenannt, Andreas;Reiher, Christopher;Strotman, Neil A.;Chen, Ke;Eastgate, Martin D.;Baran, Phil S. [Organic Letters,2013,vol. 15,# 4,p. 792 - 795]

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