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ChemicalBook CAS DataBase List 1-Bromo-4-chloro-2-methylbenzene
14495-51-3

1-Bromo-4-chloro-2-methylbenzene synthesis

4synthesis methods
-

Yield:14495-51-3 90%

Reaction Conditions:

Stage #1:amino-5-bromo-2-toluene with boron trifluoride diethyl etherate;tetraethylammonium chloride in acetonitrile at 0; for 0.166667 h;
Stage #2: with tert.-butylnitrite in acetonitrile at 0 - 20; for 1 h;

References:

Tarkhanova, Irina G.;Gantman, Michail G.;Sigeev, Alexander S.;Maslakov, Konstantin I.;Zelikman, Vladimir M.;Beletskaya, Irina P. [Mendeleev Communications,2018,vol. 28,# 3,p. 261 - 263]

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