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ChemicalBook CAS DataBase List 1,2-Dibromopropane
78-75-1

1,2-Dibromopropane synthesis

15synthesis methods
1,2-Dibromopropane is synthesized from bromopropane by bromination.
First mix bromopropane and iron powder, heat to 40-50°C, slowly add bromine, and continue to reflux for 2h after adding. Then, the iron slag was filtered off, and the filtrate was washed several times with water, once with 5% sodium carbonate solution, and then with 5% sodium thiosulfate solution to remove free bromine. Dry with anhydrous calcium chloride. Fractional distillation, collecting 139-142 ℃ fraction is the finished product of 1,2-dibromopropane.
-

Yield:-

Reaction Conditions:

with bromine for 0.0075 h;

Steps:

2

A mixture of propane and bromine having a molar ratio of 3.6:1 (propane:bromine) is passed through a glass reactor having a 3.6 mm inside diameter. The glass reactor is packed with borosilicate beads and the average residence time in the reactor is 27 s. 100% of the bromine is converted. 28% of the propylene is converted with selectivity to 1,2-dibromopropane of greater than 99%.

References:

US2006/229475,2006,A1 Location in patent:Page/Page column 5

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