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      ChemicalBook >> CAS DataBase List >> polyethyleneimine

      polyethyleneimine

      polyethyleneimine price.
      • $100 - $556
      • Product name: polyethyleneimine
      • CAS: 25987-06-8
      • MF: C4H13N3
      • MW: 103.17
      • EINECS:247-038-6
      • MDL Number:MFCD00084427
      • Synonyms:PolyethyleniMine, ethylenediaMine branched average Mw ~800 by LS, average Mn ~600 by GPC;Polyethylenimine, ethylenediamine branched;POLYETHYLENIMINE LOW MOLECULAR WEIGHT;1,2-Ethanediamine,polymerwithaziridine ;Polyethylenimine, branched average Mw ~800 by LS, average Mn ~600 by GPC;Polyethylenimine solution;Polyethylenimine, epichlorohydrin modified solution;BRANCHED POLYMER
      4 prices
      Selected condition:
      Brand
      • Sigma-Aldrich
      • TRC
      Package
      • 25g
      • 100ml
      • 250ml
      • 1l
      • ManufacturerSigma-Aldrich
      • Product number408719
      • Product descriptionPolyethylenimine, ethylenediamine branched average Mw ~800 by LS, average Mn ~600 by GPC
      • Packaging100ml
      • Price$109
      • Updated2024-03-01
      • Buy
      • ManufacturerSigma-Aldrich
      • Product number408719
      • Product descriptionPolyethylenimine, ethylenediamine branched average Mw ~800 by LS, average Mn ~600 by GPC
      • Packaging250ml
      • Price$229
      • Updated2024-03-01
      • Buy
      • ManufacturerSigma-Aldrich
      • Product number408719
      • Product descriptionPolyethylenimine, ethylenediamine branched average Mw ~800 by LS, average Mn ~600 by GPC
      • Packaging1l
      • Price$556
      • Updated2024-03-01
      • Buy
      • ManufacturerTRC
      • Product numberP688508
      • Product descriptionPolyethylenimine(Branched)(TechnicalGrade)
      • Packaging25g
      • Price$100
      • Updated2021-12-16
      • Buy
      Manufacturer Product number Product description Packaging Price Updated Buy
      Sigma-Aldrich 408719 Polyethylenimine, ethylenediamine branched average Mw ~800 by LS, average Mn ~600 by GPC 100ml $109 2024-03-01 Buy
      Sigma-Aldrich 408719 Polyethylenimine, ethylenediamine branched average Mw ~800 by LS, average Mn ~600 by GPC 250ml $229 2024-03-01 Buy
      Sigma-Aldrich 408719 Polyethylenimine, ethylenediamine branched average Mw ~800 by LS, average Mn ~600 by GPC 1l $556 2024-03-01 Buy
      TRC P688508 Polyethylenimine(Branched)(TechnicalGrade) 25g $100 2021-12-16 Buy

      Properties

      Density :1.08 g/mL at 25 °C
      vapor pressure :9 mm Hg ( 20 °C)
      refractive index :n20/D 1.5240
      Flash point :>230 °F
      solubility :Chloroform (Sparingly), DMSO (Sparingly), Methanol (Slightly)
      form :Oil
      color :Colourless
      InChI :InChI=1S/C2H8N2.C2H5N/c3-1-2-4;1-2-3-1/h1-4H2;3H,1-2H2
      InChIKey :SFLOAOINZSFFAE-UHFFFAOYSA-N
      SMILES :C(N)CN.C1NC1
      EPA Substance Registry System :1,2-Ethanediamine, polymer with aziridine (25987-06-8)

      Safety Information

      Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
      Signal word: Danger
      Hazard statements:
      Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
      H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
      H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
      H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
      Precautionary statements:
      P273 Avoid release to the environment.
      P280 Wear protective gloves/protective clothing/eye protection/face protection.

      Description

      Polyethylenimine (PEI) is a polycationic molecule that has been shown to produce efficient gene transfection in numerous cell lines in vitro without the need for an endo- somolytic agent (Fig. 1). Every third atom of PEI is a nitrogen atom, leading to a densely positively charged backbone necessary for an efficacious DNA binding. PEI enhances the cellular endocytosis of plasmids but also facil-itates their endosomal escape by buffering the endosomal compartments, leading to lysosomal osmotic swelling and disruption. Although PEI is an efficient gene transfer polymer in vitro, its cytotoxicity needs to be improved for widening its use in vivo. Used as a polyelectrolyte multilayer on charged surfaces to provide a biocompatible coating on surfaces.
      Chemical structure of polymers used for gene delivery.
      Fig. 1 Chemical structure of polymers used for gene delivery.

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