Clascoterone
|
- $32 - $9435.2
- Product name: Clascoterone
- CAS: 19608-29-8
- MF: C24H34O5
- MW: 402.52
- EINECS:685-282-9
- MDL Number:MFCD18384978
- Synonyms:17alpha-propio17-(1-oxopropoxy)pregn-4-ene-3,20-dione;CB-03-01 17alpha-propionate;Cortexolone 17-alpha-propionate;17 alpha-propionate (CB-03-01);21-Hydroxy-17-(1-oxopropoxy)pregn-4-ene-3,20-dione;(8R,9S,10R,13S,14S,17R)-17-(2-hydroxyacetyl)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl propionate;Clascoterone;CB-03-01;CORTEXOLONE 17Α-PROPIONATE;CORTEXOLONE 17 ALPHA-PROPIONATE
23 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- Crysdot
- DC Chemicals
Package
- 5mg
- 10mg
- 25mg
- 50MG
- 100mg
- 250mg
- 1G
- 50g
- ManufacturerAK Scientific
- Product number0382CT
- Product descriptionCortexolone17alpha-propionate
- Packaging10mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number0382CT
- Product descriptionCortexolone17alpha-propionate
- Packaging25mg
- Price$235
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberSHG0007230
- Product descriptionCORTEXOLONE-17-ALPHA-PROPIONATE 95.00%
- Packaging10MG
- Price$1006.58
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberSHG0007230
- Product descriptionCORTEXOLONE-17-ALPHA-PROPIONATE 95.00%
- Packaging50MG
- Price$1734.23
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberSHG0007230
- Product descriptionCORTEXOLONE-17-ALPHA-PROPIONATE 95.00%
- Packaging1G
- Price$9435.2
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3108
- Product description17alpha-propionate
- Packaging5mg
- Price$142
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3108
- Product description17alpha-propionate
- Packaging10mg
- Price$189
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3108
- Product description17alpha-propionate
- Packaging50mg
- Price$614
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3108
- Product description17alpha-propionate
- Packaging100mg
- Price$1024
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154679
- Product descriptionCB-03-01 >99%
- Packaging100mg
- Price$615.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154679
- Product descriptionCB-03-01 >99%
- Packaging250mg
- Price$1060.8
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154679
- Product descriptionCB-03-01 >99%
- Packaging1g
- Price$1802
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number28392
- Product descriptionCortexolone 17α-propionate
- Packaging5mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28392
- Product descriptionCortexolone 17α-propionate
- Packaging10mg
- Price$57
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28392
- Product descriptionCortexolone 17α-propionate
- Packaging25mg
- Price$122
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28392
- Product descriptionCortexolone 17α-propionate
- Packaging100mg
- Price$335
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 0382CT | Cortexolone17alpha-propionate | 10mg | $160 | 2021-12-16 | Buy |
| AK Scientific | 0382CT | Cortexolone17alpha-propionate | 25mg | $235 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | SHG0007230 | CORTEXOLONE-17-ALPHA-PROPIONATE 95.00% | 10MG | $1006.58 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | SHG0007230 | CORTEXOLONE-17-ALPHA-PROPIONATE 95.00% | 50MG | $1734.23 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | SHG0007230 | CORTEXOLONE-17-ALPHA-PROPIONATE 95.00% | 1G | $9435.2 | 2021-12-16 | Buy |
| ApexBio Technology | A3108 | 17alpha-propionate | 5mg | $142 | 2021-12-16 | Buy |
| ApexBio Technology | A3108 | 17alpha-propionate | 10mg | $189 | 2021-12-16 | Buy |
| ApexBio Technology | A3108 | 17alpha-propionate | 50mg | $614 | 2021-12-16 | Buy |
| ApexBio Technology | A3108 | 17alpha-propionate | 100mg | $1024 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb154679 | CB-03-01 >99% | 100mg | $615.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb154679 | CB-03-01 >99% | 250mg | $1060.8 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb154679 | CB-03-01 >99% | 1g | $1802 | 2021-12-16 | Buy |
| Cayman Chemical | 28392 | Cortexolone 17α-propionate | 5mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 28392 | Cortexolone 17α-propionate | 10mg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 28392 | Cortexolone 17α-propionate | 25mg | $122 | 2024-03-01 | Buy |
| Cayman Chemical | 28392 | Cortexolone 17α-propionate | 100mg | $335 | 2024-03-01 | Buy |
Properties
Boiling point :538.9±50.0 °C(Predicted)
Density :1.19
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :Powder
pka :12.98±0.10(Predicted)
color :White to light yellow
InChIKey :GPNHMOZDMYNCPO-PDUMRIMRSA-N
SMILES :C1(=O)C=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)[C@@](OC(=O)CC)(C(=O)CO)CC3)CC2
Density :1.19
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :Powder
pka :12.98±0.10(Predicted)
color :White to light yellow
InChIKey :GPNHMOZDMYNCPO-PDUMRIMRSA-N
SMILES :C1(=O)C=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)[C@@](OC(=O)CC)(C(=O)CO)CC3)CC2
Safety Information
| Symbol(GHS): |
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | ||||||||||||||
| Hazard statements: |
|
||||||||||||||
| Precautionary statements: |
|
Description
Clascoterone (Winlevi®) is an androgen receptor inhibitor being developed as a topical cream and solution by Cassiopea (a spin-out company of Cosmo Pharmaceuticals) for the treatment of androgen-dependent skin disorders, including androgenetic alopecia and acne vulgaris. Although the exact mechanism of action of clascoterone for the topical treatment of acne vulgaris is unknown, the drug is believed to compete with the androgen dihydrotestosterone for binding to androgen receptors in the sebaceous gland and hair follicles to attenuate signalling necessary for acne pathogenesis. In August 2020, clascoterone cream 1% received its first approval in the USA for the topical treatment of acne vulgaris in patients 12 years of age or older. Clinical studies of a different formulation of clascoterone (a solution containing a higher concentration of the drug) for the treatment of androgenetic alopecia are underway in Germany and the USA. This article summarizes the milestones in the development of clascoterone leading to this first approval for the topical treatment of acne vulgaris.More related product prices
TriethoxysilaneRelated product price
- Triethoxysilane
$30-2361.98
Suppliers and manufacturers
Tianjin Kilo Pharmaceutical Sci-Tech Co., Ltd
