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ChemicalBook >> CAS DataBase List >> YK-3-237

YK-3-237

YK-3-237 price.
  • $32 - $645
  • Product name: YK-3-237
  • CAS: 1215281-19-8
  • MF: C19H21BO7
  • MW: 372.18
  • EINECS:
  • MDL Number:
  • Synonyms:B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid;YK3237,inhibit,Sirtuin,p53,breast,cancer,triple-negative,mtp53,Mutant,TNBC,Inhibitor,deacetylation,YK 3 237;Boronic acid, B-[2-methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]-;(E)-(2-Methoxy-5-(3-oxo-3-(3,4,5-trimethoxyphenyl)prop-1-en-1-yl)phenyl)boronic acid;YK-3-237, 10 mM in DMSO
6 prices
Selected condition：
Brand
  • AK Scientific
  • Cayman Chemical
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • ManufacturerAK Scientific
  • Product numberSYN5077
  • Product descriptionYK-3-237
  • Packaging50mg
  • Price$645
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21516
  • Product descriptionYK-3-237 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21516
  • Product descriptionYK-3-237 ≥98%
  • Packaging5mg
  • Price$93
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21516
  • Product descriptionYK-3-237 ≥98%
  • Packaging10mg
  • Price$139
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21516
  • Product descriptionYK-3-237 ≥98%
  • Packaging25mg
  • Price$305
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberY120020
  • Product descriptionYK3-237
  • Packaging5mg
  • Price$75
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5077 YK-3-237 50mg $645 2021-12-16 Buy
Cayman Chemical 21516 YK-3-237 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 21516 YK-3-237 ≥98% 5mg $93 2024-03-01 Buy
Cayman Chemical 21516 YK-3-237 ≥98% 10mg $139 2024-03-01 Buy
Cayman Chemical 21516 YK-3-237 ≥98% 25mg $305 2024-03-01 Buy
TRC Y120020 YK3-237 5mg $75 2021-12-16 Buy

Properties

Boiling point :616.2±65.0 °C(Predicted)
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 10 mg/ml
form :A crystalline solid
pka :8.08±0.58(Predicted)
color :White to light yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

YK 3-237, is a sirtuin-1 (SIRT1) activator, and inhibits proliferation of breast cancer cell lines inducing G2/M cell cycle arrest and apoptosis.

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