成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Welcome to chemicalbook!
400-158-6606
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook >> CAS DataBase List >> Valrubicin

Valrubicin

Valrubicin price.
  • $45 - $2500
  • Product name: Valrubicin
  • CAS: 56124-62-0
  • MF: C34H36F3NO13
  • MW: 723.64
  • EINECS:680-664-1
  • MDL Number:MFCD01939322
  • Synonyms:ad32 ;antibioticad32 ;nsc-246131 ;n-trifluoroacetyladriamycin-14-valerate ;n-trifluoroacetyladriamycin14-valerate ;n-trifluoroacetyldoxorubicin14-valerate ;trifluoroacetyl-adriamyci14-valerate ;trifluoroacetyladriamycin-14-valerate
24 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • AvaChem
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
  • Usbiological
Package
  • 500μg
  • 1MG
  • 5mg
  • 0.01G
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberB954
  • Product descriptionValrubicin
  • Packaging25mg
  • Price$525
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA191480
  • Product description2-oxo-2-((2S,4S)-2,5,12-trihydroxy-4-(((2R,4S,5S,6S)-5-hydroxy-6-methyl-4-(2,2,2-trifluoroacetamido)tetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)ethylpentanoate 98+%
  • Packaging5mg
  • Price$194
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA191480
  • Product description2-oxo-2-((2S,4S)-2,5,12-trihydroxy-4-(((2R,4S,5S,6S)-5-hydroxy-6-methyl-4-(2,2,2-trifluoroacetamido)tetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)ethylpentanoate 98+%
  • Packaging10mg
  • Price$291
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA191480
  • Product description2-oxo-2-((2S,4S)-2,5,12-trihydroxy-4-(((2R,4S,5S,6S)-5-hydroxy-6-methyl-4-(2,2,2-trifluoroacetamido)tetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)ethylpentanoate 98+%
  • Packaging25mg
  • Price$494
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA191480
  • Product description2-oxo-2-((2S,4S)-2,5,12-trihydroxy-4-(((2R,4S,5S,6S)-5-hydroxy-6-methyl-4-(2,2,2-trifluoroacetamido)tetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)ethylpentanoate 98+%
  • Packaging50mg
  • Price$642
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0005346
  • Product descriptionVALRUBICIN 95.00%
  • Packaging1MG
  • Price$739.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0005346
  • Product descriptionVALRUBICIN 95.00%
  • Packaging0.01G
  • Price$487
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2205
  • Product descriptionValrubicin
  • Packaging1mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2205
  • Product descriptionValrubicin
  • Packaging5mg
  • Price$145
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2205
  • Product descriptionValrubicin
  • Packaging25mg
  • Price$375
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2205
  • Product descriptionValrubicin
  • Packaging100mg
  • Price$775
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number22964
  • Product descriptionValrubicin ≥98%
  • Packaging500μg
  • Price$85
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22964
  • Product descriptionValrubicin ≥98%
  • Packaging1mg
  • Price$158
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22964
  • Product descriptionValrubicin ≥98%
  • Packaging5mg
  • Price$661
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2929
  • Product descriptionValrubicin 99.95%
  • Packaging10mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2929
  • Product descriptionValrubicin 99.95%
  • Packaging50mg
  • Price$780
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific B954 Valrubicin 25mg $525 2021-12-16 Buy
Ambeed A191480 2-oxo-2-((2S,4S)-2,5,12-trihydroxy-4-(((2R,4S,5S,6S)-5-hydroxy-6-methyl-4-(2,2,2-trifluoroacetamido)tetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)ethylpentanoate 98+% 5mg $194 2021-12-16 Buy
Ambeed A191480 2-oxo-2-((2S,4S)-2,5,12-trihydroxy-4-(((2R,4S,5S,6S)-5-hydroxy-6-methyl-4-(2,2,2-trifluoroacetamido)tetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)ethylpentanoate 98+% 10mg $291 2021-12-16 Buy
Ambeed A191480 2-oxo-2-((2S,4S)-2,5,12-trihydroxy-4-(((2R,4S,5S,6S)-5-hydroxy-6-methyl-4-(2,2,2-trifluoroacetamido)tetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)ethylpentanoate 98+% 25mg $494 2021-12-16 Buy
Ambeed A191480 2-oxo-2-((2S,4S)-2,5,12-trihydroxy-4-(((2R,4S,5S,6S)-5-hydroxy-6-methyl-4-(2,2,2-trifluoroacetamido)tetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)ethylpentanoate 98+% 50mg $642 2021-12-16 Buy
American Custom Chemicals Corporation API0005346 VALRUBICIN 95.00% 1MG $739.2 2021-12-16 Buy
American Custom Chemicals Corporation API0005346 VALRUBICIN 95.00% 0.01G $487 2021-12-16 Buy
AvaChem 2205 Valrubicin 1mg $45 2021-12-16 Buy
AvaChem 2205 Valrubicin 5mg $145 2021-12-16 Buy
AvaChem 2205 Valrubicin 25mg $375 2021-12-16 Buy
AvaChem 2205 Valrubicin 100mg $775 2021-12-16 Buy
Cayman Chemical 22964 Valrubicin ≥98% 500μg $85 2024-03-01 Buy
Cayman Chemical 22964 Valrubicin ≥98% 1mg $158 2024-03-01 Buy
Cayman Chemical 22964 Valrubicin ≥98% 5mg $661 2024-03-01 Buy
ChemScene CS-2929 Valrubicin 99.95% 10mg $300 2021-12-16 Buy
ChemScene CS-2929 Valrubicin 99.95% 50mg $780 2021-12-16 Buy

Properties

Melting point :116-117 °C
Boiling point :135-136 C
Density :1.3473 (estimate)
storage temp. :2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :7.34±0.60(Predicted)
color :Red
Water Solubility :insoluble
InChIKey :ZOCKGBMQLCSHFP-XGMQQLFPNA-N
SMILES :C12=C(O)C3=C(C(=O)C4C=CC=C(OC)C=4C3=O)C(O)=C1C[C@@](O)(C(=O)COC(=O)CCCC)C[C@@H]2O[C@@H]1O[C@H]([C@@H](O)[C@@H](NC(=O)C(F)(F)F)C1)C |&1:21,34,36,38,39,41,r|

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H340 May cause genetic defects Germ cell mutagenicity Category 1A, 1B Danger GHS hazard pictograms
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P281 Use personal protective equipment as required.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P322 Specific measures (see …on this label).
P330 Rinse mouth.
P363 Wash contaminated clothing before reuse.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Valrubicin was launched as a new 'chemotherapeutic agent for the treatment of bladder cancer, particularly in patients with BCG-refractory carcinoma in situ (CIS) of the bladder for whom immediate cystectomy is unacceptable. It belongs to the class of anthracyclines, the widest used in human cancers, and is a N-trifluoroacetyl 14-valerate derivative of doxorubicin.Valrubicin can be obtained in 3 steps from daunomycin by N-trifluoroacetylation of the sugar moiety then iodination of the 2-acetyl group and introduction of a valerate residue. A proposed mechanism involved in the cytotoxicity of Valrubicin coud be the blockade of SV40 large T antigen helicase; this cellular enzyme is involved in the formation of a ternary complex with DNA to maintain the topographic structure of DNA during transcription. In patients with CIS of bladder refractory to front line and second line therapies, intravesical instillation of Valrubicin resulted in a complete response with a significant rate and allowed a delay in cystectomy. Systemic absorption was minimal and accordingly produced a lower incidence of cardiotoxicity compared with doxorubicin.

Related product price