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ChemicalBook >> CAS DataBase List >> Tolnaftate

Tolnaftate

Tolnaftate price.
  • $6 - $3418.8
  • Product name: Tolnaftate
  • CAS: 2398-96-1
  • MF: C19H17NOS
  • MW: 307.41
  • EINECS:219-266-6
  • MDL Number:MFCD00056611
  • Synonyms:2-naphthyl n-methyl-n-(3-tolyl)thionocarbamate;METHYL 3-TOLYLTHIOCARBAMIC ACID O-NAPHTHALEN-2-YL ESTER;METHYL-[3-METHYLPHENYL]-CARBAMOTHIOIC ACID O-2-NAPHTHYL ESTER;Aftate;Carbamothioic acid, methyl(3-methylphenyl)-, O-2-naphthalenyl ester;Carbanilic acid, m,N-dimethylthio-, O-2-naphthyl ester;Carbanilic acid, N,m-dimethylthio-, O-2-naphthyl ester;Chinofungin
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  • AK Scientific
  • Alfa Aesar
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  • American Custom Chemicals Corporation
  • Aronis compounds
  • Cayman Chemical
  • Chem-Impex
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  • Matrix Scientific
  • Sigma-Aldrich
  • TCI Chemical
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  • 10g
  • 25g
  • 50G
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  • ManufacturerAK Scientific
  • Product numberJ50201
  • Product descriptionTolnaftate
  • Packaging25g
  • Price$413
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberQ770
  • Product descriptionTolnaftate
  • Packaging25g
  • Price$551
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61834
  • Product descriptionTolnaftate
  • Packaging1g
  • Price$63
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61834
  • Product descriptionTolnaftate
  • Packaging5g
  • Price$198
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61834
  • Product descriptionTolnaftate
  • Packaging25g
  • Price$685
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA357832
  • Product descriptionO-Naphthalen-2-ylmethyl(m-tolyl)carbamothioate 98+%
  • Packaging250mg
  • Price$6
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA357832
  • Product descriptionO-Naphthalen-2-ylmethyl(m-tolyl)carbamothioate 98+%
  • Packaging1g
  • Price$11
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA357832
  • Product descriptionO-Naphthalen-2-ylmethyl(m-tolyl)carbamothioate 98+%
  • Packaging5g
  • Price$21
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA357832
  • Product descriptionO-Naphthalen-2-ylmethyl(m-tolyl)carbamothioate 98+%
  • Packaging25g
  • Price$72
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA357832
  • Product descriptionO-Naphthalen-2-ylmethyl(m-tolyl)carbamothioate 98+%
  • Packaging100g
  • Price$237
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004445
  • Product descriptionTOLNAFTATE 95.00%
  • Packaging50G
  • Price$3418.8
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004445
  • Product descriptionTOLNAFTATE 95.00%
  • Packaging5G
  • Price$889.35
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004445
  • Product descriptionTOLNAFTATE 95.00%
  • Packaging1G
  • Price$149.1
  • Updated2021-12-16
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  • ManufacturerAronis compounds
  • Product numberc07915
  • Product descriptionO-2-naphthylmethyl(3-methylphenyl)thiocarbamate
  • Packaging10mg
  • Price$20
  • Updated2021-12-16
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  • ManufacturerAronis compounds
  • Product numberc07915
  • Product descriptionO-2-naphthylmethyl(3-methylphenyl)thiocarbamate
  • Packaging50mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerAronis compounds
  • Product numberc07915
  • Product descriptionO-2-naphthylmethyl(3-methylphenyl)thiocarbamate
  • Packaging100mg
  • Price$80
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J50201 Tolnaftate 25g $413 2021-12-16 Buy
AK Scientific Q770 Tolnaftate 25g $551 2021-12-16 Buy
Alfa Aesar J61834 Tolnaftate 1g $63 2024-03-01 Buy
Alfa Aesar J61834 Tolnaftate 5g $198 2024-03-01 Buy
Alfa Aesar J61834 Tolnaftate 25g $685 2024-03-01 Buy
Ambeed A357832 O-Naphthalen-2-ylmethyl(m-tolyl)carbamothioate 98+% 250mg $6 2021-12-16 Buy
Ambeed A357832 O-Naphthalen-2-ylmethyl(m-tolyl)carbamothioate 98+% 1g $11 2021-12-16 Buy
Ambeed A357832 O-Naphthalen-2-ylmethyl(m-tolyl)carbamothioate 98+% 5g $21 2021-12-16 Buy
Ambeed A357832 O-Naphthalen-2-ylmethyl(m-tolyl)carbamothioate 98+% 25g $72 2021-12-16 Buy
Ambeed A357832 O-Naphthalen-2-ylmethyl(m-tolyl)carbamothioate 98+% 100g $237 2021-12-16 Buy
American Custom Chemicals Corporation API0004445 TOLNAFTATE 95.00% 50G $3418.8 2021-12-16 Buy
American Custom Chemicals Corporation API0004445 TOLNAFTATE 95.00% 5G $889.35 2021-12-16 Buy
American Custom Chemicals Corporation API0004445 TOLNAFTATE 95.00% 1G $149.1 2021-12-16 Buy
Aronis compounds c07915 O-2-naphthylmethyl(3-methylphenyl)thiocarbamate 10mg $20 2021-12-16 Buy
Aronis compounds c07915 O-2-naphthylmethyl(3-methylphenyl)thiocarbamate 50mg $50 2021-12-16 Buy
Aronis compounds c07915 O-2-naphthylmethyl(3-methylphenyl)thiocarbamate 100mg $80 2021-12-16 Buy

Properties

Melting point :110.5-111.5°C
Boiling point :453.4±38.0 °C(Predicted)
Density :1.1328 (rough estimate)
refractive index :1.6970 (estimate)
storage temp. :Sealed in dry,2-8°C
solubility :Soluble in chloroform at 50 mg/ml. Sparingly soluble in ethanol or methanol
form :powder
pka :-0.35±0.50(Predicted)
color :white to off-white
Water Solubility :<0.1 g/100 mL at 22 ºC
λmax :258nm(MeOH)(lit.)
Merck :14,9519
InChIKey :FUSNMLFNXJSCDI-UHFFFAOYSA-N
LogP :5.142 (est)
NIST Chemistry Reference :Tolnaftate(2398-96-1)
EPA Substance Registry System :Tolnaftate (2398-96-1)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Tolnaftate is used to study the mechanism of ergosterol (sterol) biosynthesis at the rate-limiting step of squalene epoxidase inhibition. Tolnaftate is clinically used to treat cutaneous infections such as athlete?s foot, jock itch, and ringworm1. It also has been used as a comparator compound for antifungal efficiency studies.

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