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ChemicalBook >> CAS DataBase List >> TYRPHOSTIN AG 1296

TYRPHOSTIN AG 1296

TYRPHOSTIN AG 1296 price.
  • $11 - $2709
  • Product name: TYRPHOSTIN AG 1296
  • CAS: 146535-11-7
  • MF: C16H14N2O2
  • MW: 266.29
  • EINECS:
  • MDL Number:MFCD00270913
  • Synonyms:TYRPHOSTIN AG 1296;AG 1296;6,7-DIMETHOXY-2-PHENYLQUINOXALINE;6,7-DIMETHOXY-3-PHENYLQUINOXALINE;Quinoxaline,6,7-dimethoxy-2-phenyl-;AG-1296;AG 1296;;AG 1296 - CAS 146535-11-7 - Calbiochem;AG-1296 (Tyrphostin AG 1296)
28 prices
Selected condition：
Brand
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • TRC
Package
  • 1MG
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 5g
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product number2090AH
  • Product descriptionTyrphostin AG-1296
  • Packaging25mg
  • Price$361
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67039
  • Product descriptionTyrphostin AG-1296 98%
  • Packaging5mg
  • Price$182
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA104725
  • Product descriptionAG 1296 99+%
  • Packaging5mg
  • Price$11
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA104725
  • Product descriptionAG 1296 99+%
  • Packaging10mg
  • Price$17
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA104725
  • Product descriptionAG 1296 99+%
  • Packaging25mg
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA104725
  • Product descriptionAG 1296 99+%
  • Packaging250mg
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA104725
  • Product descriptionAG 1296 99+%
  • Packaging1g
  • Price$259
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000651
  • Product descriptionTYRPHOSTIN AG-1296 95.00%
  • Packaging1MG
  • Price$432
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000651
  • Product descriptionTYRPHOSTIN AG-1296 95.00%
  • Packaging5MG
  • Price$658.12
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000651
  • Product descriptionTYRPHOSTIN AG-1296 95.00%
  • Packaging25MG
  • Price$864.7
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2477
  • Product descriptionTyrphostin AG-1296
  • Packaging10mM(in 1mL DMSO)
  • Price$112
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS427669
  • Product descriptionAG 1296 ≥99%
  • Packaging25mg
  • Price$468
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010592
  • Product descriptionAG 1296 >98%
  • Packaging1mg
  • Price$28
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010592
  • Product descriptionAG 1296 >98%
  • Packaging5mg
  • Price$117
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010592
  • Product descriptionAG 1296 >98%
  • Packaging10mg
  • Price$207
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010592
  • Product descriptionAG 1296 >98%
  • Packaging25mg
  • Price$448
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2090AH Tyrphostin AG-1296 25mg $361 2021-12-16 Buy
Alfa Aesar J67039 Tyrphostin AG-1296 98% 5mg $182 2021-12-16 Buy
Ambeed A104725 AG 1296 99+% 5mg $11 2021-12-16 Buy
Ambeed A104725 AG 1296 99+% 10mg $17 2021-12-16 Buy
Ambeed A104725 AG 1296 99+% 25mg $28 2021-12-16 Buy
Ambeed A104725 AG 1296 99+% 250mg $105 2021-12-16 Buy
Ambeed A104725 AG 1296 99+% 1g $259 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000651 TYRPHOSTIN AG-1296 95.00% 1MG $432 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000651 TYRPHOSTIN AG-1296 95.00% 5MG $658.12 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000651 TYRPHOSTIN AG-1296 95.00% 25MG $864.7 2021-12-16 Buy
ApexBio Technology A2477 Tyrphostin AG-1296 10mM(in 1mL DMSO) $112 2021-12-16 Buy
Arctom AS427669 AG 1296 ≥99% 25mg $468 2021-12-16 Buy
Cayman Chemical 10010592 AG 1296 >98% 1mg $28 2024-03-01 Buy
Cayman Chemical 10010592 AG 1296 >98% 5mg $117 2024-03-01 Buy
Cayman Chemical 10010592 AG 1296 >98% 10mg $207 2024-03-01 Buy
Cayman Chemical 10010592 AG 1296 >98% 25mg $448 2024-03-01 Buy

Properties

Boiling point :420.2±40.0 °C(Predicted)
Density :1.192±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in DMSO.
pka :0.48±0.30(Predicted)
form :White solid
color :Yellow
Sensitive :Light Sensitive
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

AG-1296 is a potent and selective inhibitor of PDGFR kinase (IC50= 0.4 μM) both in vitro and in cells (Swiss 3T3 cells). This compound also inhibits Bek (FGF receptor) tyrosine kinase and c-kit. Treatment of sis oncogene transfected NIH3T3 cells with AG-1296 reverses the transformed phenotype. It also induces apoptosis in a small-cell lung cancer cell line (H526). AG-1296 is an inhibitor of Tyrosine Kinase. AG-1296 is an inhibitor of PDGFR-α and PDGFR-β.

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