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ChemicalBook >> CAS DataBase List >> TMP269

TMP269

TMP269 price.
  • $37 - $2121
  • Product name: TMP269
  • CAS: 1314890-29-3
  • MF: C25H21F3N4O3S
  • MW: 514.52
  • EINECS:
  • MDL Number:MFCD26522023
  • Synonyms:N-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide TMP269;TMP269 N-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide;BenzaMide, N-[[tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]Methyl]-3-[5-(trifluoroMethyl)-1,2,4-oxadiazol-3-yl]-;TMP269;N-((4-(4-phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)Methyl)-3-(5-(trifluoroMethyl)-1,2,4-oxadiazol-3-yl)benzaMide;N-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide;TMP269, >=98%;N-((4-(4-Phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxad
20 prices
Selected condition：
Brand
  • Absolute Chiral
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • TRC
Package
  • 10mM(in 1mL DMSO)
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 1g
  • ManufacturerAbsolute Chiral
  • Product numberO1152-00-N
  • Product descriptionN-((4-(4-phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide 95%
  • Packaging25mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2760AH
  • Product descriptionN-((4-(4-Phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide
  • Packaging1g
  • Price$2121
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2760AH
  • Product descriptionN-((4-(4-Phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide
  • Packaging250mg
  • Price$925
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8806
  • Product descriptionTMP269
  • Packaging5mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8806
  • Product descriptionTMP269
  • Packaging10mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8806
  • Product descriptionTMP269
  • Packaging10mM(in 1mL DMSO)
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17738
  • Product descriptionTMP269 ≥95%
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17738
  • Product descriptionTMP269 ≥95%
  • Packaging5mg
  • Price$151
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17738
  • Product descriptionTMP269 ≥95%
  • Packaging10mg
  • Price$266
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2463
  • Product descriptionTMP269 98.74%
  • Packaging10mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2463
  • Product descriptionTMP269 98.74%
  • Packaging50mg
  • Price$540
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2463
  • Product descriptionTMP269 98.74%
  • Packaging100mg
  • Price$1020
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2463
  • Product descriptionTMP269 98.74%
  • Packaging200mg
  • Price$1320
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003909
  • Product descriptionTMP269 98+%
  • Packaging250mg
  • Price$1202
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003909
  • Product descriptionTMP269 98+%
  • Packaging100mg
  • Price$707
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003909
  • Product descriptionTMP269 98+%
  • Packaging50mg
  • Price$416
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Absolute Chiral O1152-00-N N-((4-(4-phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide 95% 25mg $150 2021-12-16 Buy
AK Scientific 2760AH N-((4-(4-Phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide 1g $2121 2021-12-16 Buy
AK Scientific 2760AH N-((4-(4-Phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide 250mg $925 2021-12-16 Buy
ApexBio Technology A8806 TMP269 5mg $110 2021-12-16 Buy
ApexBio Technology A8806 TMP269 10mg $180 2021-12-16 Buy
ApexBio Technology A8806 TMP269 10mM(in 1mL DMSO) $180 2021-12-16 Buy
Cayman Chemical 17738 TMP269 ≥95% 1mg $37 2024-03-01 Buy
Cayman Chemical 17738 TMP269 ≥95% 5mg $151 2024-03-01 Buy
Cayman Chemical 17738 TMP269 ≥95% 10mg $266 2024-03-01 Buy
ChemScene CS-2463 TMP269 98.74% 10mg $180 2021-12-16 Buy
ChemScene CS-2463 TMP269 98.74% 50mg $540 2021-12-16 Buy
ChemScene CS-2463 TMP269 98.74% 100mg $1020 2021-12-16 Buy
ChemScene CS-2463 TMP269 98.74% 200mg $1320 2021-12-16 Buy
Crysdot CD31003909 TMP269 98+% 250mg $1202 2021-12-16 Buy
Crysdot CD31003909 TMP269 98+% 100mg $707 2021-12-16 Buy
Crysdot CD31003909 TMP269 98+% 50mg $416 2021-12-16 Buy

Properties

Density :1.347±0.06 g/cm3(Predicted)
storage temp. :Amber Vial, -20°C Freezer, Under inert atmosphere
solubility :≥23 mg/mL in DMSO; insoluble in H2O; ≥21 mg/mL in EtOH with ultrasonic
form :solid
pka :13.66±0.46(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P501 Dispose of contents/container to..…

Description

While class I HDACs are localized predominantly within the nucleus, class II HDACs shuttle into and out of the nucleus in response to intracellular signaling. Class IIa HDACs, which include HDAC4, 5, 7, and 9, commonly act as corepressors and play diverse roles in cell biology. TMP269 is a cell-permeable inhibitor of class IIa HDACs (IC50s = 126, 80, 36, and 19 nM for HDAC4, 5, 7, and 9, respectively). It contains a metal-binding group, trifluoromethyloxadiazole that confers selectivity for class IIa HDACs.

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