SGC-GAK-1
|
- $75 - $4023.9
- Product name: SGC-GAK-1
- CAS: 2226517-76-4
- MF: C18H17BrN2O3
- MW: 389.24
- EINECS:
- MDL Number:MFCD31689258
- Synonyms:SGC-GAK-1;GAK INHIBITOR 1;6-Bromo-N-(3,4,5-trimethoxyphenyl)-4-quinolinamine;4-Quinolinamine, 6-bromo-N-(3,4,5-trimethoxyphenyl)-;6-Bromo-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine;SGCGAK1,Inhibitor,SGC GAK 1,inhibit;S C- AK-1
16 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- Biorbyt Ltd
- Biosynth Carbosynth
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
Package
- 5
- 5mg
- 1mg
- 25
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number8008EL
- Product descriptionSgc-gak-1
- Packaging5mg
- Price$170
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA1142890
- Product description6-Bromo-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine 98%
- Packaging5mg
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA1142890
- Product description6-Bromo-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine 98%
- Packaging10mg
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb573233
- Product descriptionSGC-GAK-1 >98%
- Packaging100mg
- Price$1208.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb573233
- Product descriptionSGC-GAK-1 >98%
- Packaging250mg
- Price$2023
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb573233
- Product descriptionSGC-GAK-1 >98%
- Packaging1g
- Price$4023.9
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB166265
- Product descriptionSGC GAK 1 NEW
- Packaging10mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB166265
- Product descriptionSGC GAK 1 NEW
- Packaging50mg
- Price$262.5
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC12565
- Product descriptionSGC-GAK-1 >98%
- Packaging100mg
- Price$800
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC12565
- Product descriptionSGC-GAK-1 >98%
- Packaging250mg
- Price$1350
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC12565
- Product descriptionSGC-GAK-1 >98%
- Packaging1g
- Price$2700
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML2202
- Product descriptionSGC-GAK-1 ≥98% (HPLC)
- Packaging5mg
- Price$105
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML2202
- Product descriptionSGC-GAK-1 ≥98% (HPLC)
- Packaging25mg
- Price$424
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number6564
- Product descriptionSGCGAK1 ≥99%(HPLC)
- Packaging5
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number6564
- Product descriptionSGCGAK1 ≥99%(HPLC)
- Packaging25
- Price$311
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberS282318
- Product descriptionSGCGAK1
- Packaging1mg
- Price$75
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 8008EL | Sgc-gak-1 | 5mg | $170 | 2021-12-16 | Buy |
| Ambeed | A1142890 | 6-Bromo-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine 98% | 5mg | $420 | 2021-12-16 | Buy |
| Ambeed | A1142890 | 6-Bromo-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine 98% | 10mg | $420 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb573233 | SGC-GAK-1 >98% | 100mg | $1208.7 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb573233 | SGC-GAK-1 >98% | 250mg | $2023 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb573233 | SGC-GAK-1 >98% | 1g | $4023.9 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB166265 | SGC GAK 1 NEW | 10mg | $75 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB166265 | SGC GAK 1 NEW | 50mg | $262.5 | 2021-12-16 | Buy |
| DC Chemicals | DC12565 | SGC-GAK-1 >98% | 100mg | $800 | 2021-12-16 | Buy |
| DC Chemicals | DC12565 | SGC-GAK-1 >98% | 250mg | $1350 | 2021-12-16 | Buy |
| DC Chemicals | DC12565 | SGC-GAK-1 >98% | 1g | $2700 | 2021-12-16 | Buy |
| Sigma-Aldrich | SML2202 | SGC-GAK-1 ≥98% (HPLC) | 5mg | $105 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML2202 | SGC-GAK-1 ≥98% (HPLC) | 25mg | $424 | 2024-03-01 | Buy |
| Tocris | 6564 | SGCGAK1 ≥99%(HPLC) | 5 | $80 | 2021-12-16 | Buy |
| Tocris | 6564 | SGCGAK1 ≥99%(HPLC) | 25 | $311 | 2021-12-16 | Buy |
| TRC | S282318 | SGCGAK1 | 1mg | $75 | 2021-12-16 | Buy |
Properties
Boiling point :484.9±45.0 °C(Predicted)
Density :1.436±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to 10 mg/ml)
pka :6.43±0.49(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
Density :1.436±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to 10 mg/ml)
pka :6.43±0.49(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
Safety Information
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Description
SGC-GAK-1 (2226517-76-4) is a highly potent and selective inhibitor of cyclin G associated kinase (GAK), a member of the numb-associated kinase (NAK) family involved in membrane trafficking and sorting of proteins and is required for the maintenance of centrosome maturation and progression though mitosis. KD?= 1.9 nM with >50-fold selectivity against a panel of 400 kinases. It also displayed affinity for RIPK2 (KD?= 110 nM) and ADCK3 (KD?= 190 nM). SGC-GAK-1 displayed potent cellular activity in HEK293T cells (IC50?= 120 nM) and showed strong growth inhibition in the prostate cancer cell lines LNCaP (IC50?= 0.65 μM) and 22Rv1 (IC50?= 0.17 μM).Related product price
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