SENEGENIN
- $24 - $1075
- Product name: SENEGENIN
- CAS: 2469-34-3
- MF: C30H45ClO6
- MW: 537.13
- EINECS:
- MDL Number:MFCD00466906
- Synonyms:SENEGENIN;SENEGIN;28-dioicacid,12-(chloromethyl)-2-beta,3-beta-dihydroxy-27-noro-13-ene-2 ;27-Norolean-13-ene-23,28-dioicacid, 12-(chloromethyl)-2,3-dihydroxy-, (2β,3β,4α,12α)-;Tenuigenin;12α-(Chloromethyl)-2β,3β-dihydroxy-27-nor-5α-olean-13-ene-23,28-dioic acid;12α-Chloromethyl-2β,3β-dihydroxy-27-norolean-1-ene-23,28-dioic acid;Tenuifolic acid
27 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- JR MediChem
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 1mg
- 5MG
- 10mg
- 20mg
- 25mg
- 100mg
- ManufacturerAK Scientific
- Product numberX1228
- Product descriptionSenegenin
- Packaging1mg
- Price$24
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX1228
- Product descriptionSenegenin
- Packaging25mg
- Price$280
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPXT0000589
- Product descriptionSENEGENIN 95.00%
- Packaging5MG
- Price$742.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN1749
- Product descriptionSenegenin
- Packaging20mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN99109
- Product descriptionSenegenin ≥98%
- Packaging20mg
- Price$128
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2080
- Product descriptionTenuigenin
- Packaging5mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2080
- Product descriptionTenuigenin
- Packaging20mg
- Price$195
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2080
- Product descriptionTenuigenin
- Packaging100mg
- Price$690
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb594287
- Product descriptionSenegenin
- Packaging20mg
- Price$289
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb594287
- Product descriptionSenegenin
- Packaging100mg
- Price$530.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb105686
- Product descriptionTenuigenin >98%,Standard References Grade
- Packaging20mg
- Price$569.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number28824
- Product descriptionTenuigenin
- Packaging100mg
- Price$975
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28824
- Product descriptionTenuigenin
- Packaging25mg
- Price$338
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28824
- Product descriptionTenuigenin
- Packaging10mg
- Price$143
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28824
- Product descriptionTenuigenin
- Packaging5mg
- Price$75
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0009808
- Product descriptionTenuigenin 99.24%
- Packaging5mg
- Price$60
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | X1228 | Senegenin | 1mg | $24 | 2021-12-16 | Buy |
AK Scientific | X1228 | Senegenin | 25mg | $280 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | PXT0000589 | SENEGENIN 95.00% | 5MG | $742.5 | 2021-12-16 | Buy |
ApexBio Technology | N1749 | Senegenin | 20mg | $200 | 2021-12-16 | Buy |
Arctom | CFN99109 | Senegenin ≥98% | 20mg | $128 | 2021-12-16 | Buy |
AvaChem | 2080 | Tenuigenin | 5mg | $75 | 2021-12-16 | Buy |
AvaChem | 2080 | Tenuigenin | 20mg | $195 | 2021-12-16 | Buy |
AvaChem | 2080 | Tenuigenin | 100mg | $690 | 2021-12-16 | Buy |
Biorbyt Ltd | orb594287 | Senegenin | 20mg | $289 | 2021-12-16 | Buy |
Biorbyt Ltd | orb594287 | Senegenin | 100mg | $530.4 | 2021-12-16 | Buy |
Biorbyt Ltd | orb105686 | Tenuigenin >98%,Standard References Grade | 20mg | $569.5 | 2021-12-16 | Buy |
Cayman Chemical | 28824 | Tenuigenin | 100mg | $975 | 2024-03-01 | Buy |
Cayman Chemical | 28824 | Tenuigenin | 25mg | $338 | 2024-03-01 | Buy |
Cayman Chemical | 28824 | Tenuigenin | 10mg | $143 | 2024-03-01 | Buy |
Cayman Chemical | 28824 | Tenuigenin | 5mg | $75 | 2024-03-01 | Buy |
ChemScene | CS-0009808 | Tenuigenin 99.24% | 5mg | $60 | 2021-12-16 | Buy |
Properties
Melting point :290-292℃
alpha :D +19° (c = 0.70 in ethanol)
Boiling point :674.1±55.0 °C(Predicted)
Density :1.28
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :4.27±0.70(Predicted)
form :powder
color :white to beige
alpha :D +19° (c = 0.70 in ethanol)
Boiling point :674.1±55.0 °C(Predicted)
Density :1.28
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :4.27±0.70(Predicted)
form :powder
color :white to beige
Safety Information
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Signal word: | Warning | ||||||||||||||
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Description
Tenuigenin is a triterpenoid sapogenin that has been found in P. tenuifolia and has diverse biological activities, including antioxidant, anti-inflammatory, and neuroprotective properties. It inhibits IL-1β and reactive oxygen species (ROS) production from LPS-induced mouse BV2 microglia at a concentration of 4 μM. Tenuigenin (25 mg/kg per day) decreases NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome activation and prevents dopaminergic neuronal degeneration in the mouse substantia nigra pars compacta in an MPTP-induced model of Parkinson''s disease. Tenuigenin (2 mg/kg) also reduces increases in lung edema and the levels of IL-1β and TNF-α in bronchoalveolar lavage fluid (BALF) in a mouse model of intranasal S. aureus-induced pneumonia.Related product price
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