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ChemicalBook >> CAS DataBase List >> Rosuvastatin calcium

Rosuvastatin calcium

Rosuvastatin calcium price.
  • $6 - $1802
  • Product name: Rosuvastatin calcium
  • CAS: 147098-20-2
  • MF: C22H30CaFN3O6S
  • MW: 523.63
  • EINECS:627-028-1
  • MDL Number:MFCD04112702
  • Synonyms:(+)-bis[7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3R,5S-dihydroxy-6(E)-heptenoic acid]calcium salt;calcium (3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethan-3-ylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate;ZD4522;(3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[N-methyl(n-methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-Hep;Rosuvastatin (as Ca salt);ROSUVASTATIN, CALCIUM SALT;ROSUVASTATIN CALCIUM;Calcium (3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-y
45 prices
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Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
Package
  • 25mg
  • 100mg
  • 200MG
  • 10g
  • 10
  • 50
  • Y0001721
  • 300MG
  • 10mM(in 1mL DMSO)
  • 5MG
  • 10mg
  • 50mg
  • 250mg
  • 1g
  • 5g
  • 25g
  • 100g
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3728-M050
  • Product descriptionRosuvastatin.calciumsalt ≥98%(HPLC)
  • Packaging50mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberF360
  • Product descriptionRosuvastatin Calcium
  • Packaging250mg
  • Price$127
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ52701
  • Product descriptionRosuvastatin Calcium
  • Packaging5g
  • Price$693
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ20649
  • Product descriptionRosuvastatin Calcium
  • Packaging5g
  • Price$911
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA272688
  • Product descriptionCalcium(3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate 98%
  • Packaging10mg
  • Price$6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA272688
  • Product descriptionCalcium(3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate 98%
  • Packaging1g
  • Price$16
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA272688
  • Product descriptionCalcium(3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate 98%
  • Packaging5g
  • Price$53
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA272688
  • Product descriptionCalcium(3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate 98%
  • Packaging25g
  • Price$185
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA272688
  • Product descriptionCalcium(3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate 98%
  • Packaging100g
  • Price$605
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0025993
  • Product descriptionROSUVASTATIN CALCIUM 95.00%
  • Packaging5MG
  • Price$167.2
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8518
  • Product descriptionRosuvastatin Calcium
  • Packaging10mM(in 1mL DMSO)
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8518
  • Product descriptionRosuvastatin Calcium
  • Packaging50mg
  • Price$116
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8518
  • Product descriptionRosuvastatin Calcium
  • Packaging100mg
  • Price$147
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2169
  • Product descriptionRosuvastatin Calcium
  • Packaging25mg
  • Price$79
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2169
  • Product descriptionRosuvastatin Calcium
  • Packaging100mg
  • Price$115
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2169
  • Product descriptionRosuvastatin Calcium
  • Packaging1g
  • Price$279
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-3728-M050 Rosuvastatin.calciumsalt ≥98%(HPLC) 50mg $50 2021-12-16 Buy
AK Scientific F360 Rosuvastatin Calcium 250mg $127 2021-12-16 Buy
AK Scientific J52701 Rosuvastatin Calcium 5g $693 2021-12-16 Buy
AK Scientific J20649 Rosuvastatin Calcium 5g $911 2021-12-16 Buy
Ambeed A272688 Calcium(3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate 98% 10mg $6 2021-12-16 Buy
Ambeed A272688 Calcium(3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate 98% 1g $16 2021-12-16 Buy
Ambeed A272688 Calcium(3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate 98% 5g $53 2021-12-16 Buy
Ambeed A272688 Calcium(3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate 98% 25g $185 2021-12-16 Buy
Ambeed A272688 Calcium(3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate 98% 100g $605 2021-12-16 Buy
American Custom Chemicals Corporation API0025993 ROSUVASTATIN CALCIUM 95.00% 5MG $167.2 2021-12-16 Buy
ApexBio Technology A8518 Rosuvastatin Calcium 10mM(in 1mL DMSO) $80 2021-12-16 Buy
ApexBio Technology A8518 Rosuvastatin Calcium 50mg $116 2021-12-16 Buy
ApexBio Technology A8518 Rosuvastatin Calcium 100mg $147 2021-12-16 Buy
AvaChem 2169 Rosuvastatin Calcium 25mg $79 2021-12-16 Buy
AvaChem 2169 Rosuvastatin Calcium 100mg $115 2021-12-16 Buy
AvaChem 2169 Rosuvastatin Calcium 1g $279 2021-12-16 Buy

Properties

Melting point :122°C
alpha :D24 +14.8° (c = 1.012 in 50% methanol)
storage temp. :2-8°C
solubility :DMSO : 25 mg/mL (49.94 mM; Need ultrasonic)H2O : 1 mg/mL (2.00 mM; Need ultrasonic)
form :powder
color :white to beige
optical activity :[α]/D +12 to +18°, c = 1 in methanol: water (1:1)
λmax :243nm(Phosphate buffer sol.)(lit.)
Merck :14,8270
InChIKey :JSVIQRTVYKCCOM-LMRKSJJTNA-N
SMILES :C(/C1=C(N=C(N(C)S(=O)(=O)C)N=C1C1C=CC(F)=CC=1)C(C)C)=C\[C@@H](O)C[C@@H](O)CC(=O)O.[Ca] |&1:24,27,r|
CAS DataBase Reference :147098-20-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase is the rate-limiting enzyme in the cholesterol biosynthetic pathway and the target of the “statin” class of cholesterol-lowering drugs. Rosuvastatin is an HMG-CoA reductase inhibitor (IC50 = 5 nM). It is a fully-synthetic inhibitor that is designed to maximize the points of contact with, and inhibition of, HMG-CoA reductase. Rosuvastatin reduces low-density lipoprotein and C-reactive protein and increases high-density lipoprotein in clinical trials.

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