Pimodivir
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- $90 - $2700
- Product name: Pimodivir
- CAS: 1629869-44-8
- MF: C20H19F2N5O2
- MW: 399.39
- EINECS:
- MDL Number:MFCD31382121
- Synonyms:Pimodivir;Pimodivir (VX-787);VX-787;VRT0928787;VRT-0928787;VX-787; VX 787; VX787; JNJ-872; JNJ 872; JNJ872; VRT-0928787; VRT 0928787; VRT0928787;PIMODIVIR;VX-787 (Pimodivir);Bicyclo[2.2.2]octane-2-carboxylic acid, 3-[[5-fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]-, (2S,3S)-
9 prices
Selected condition：
Brand
- AHH
- Cayman Chemical
- ChemScene
- DC Chemicals
- TRC
Package
- 5mg
- 10mg
- 25mg
- 1g
- ManufacturerAHH
- Product numberAPI-1946
- Product descriptionVX787 VX787
- Packaging1g
- Price$2300
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number29321
- Product descriptionPimodivir
- Packaging25mg
- Price$343
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29321
- Product descriptionPimodivir
- Packaging10mg
- Price$146
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29321
- Product descriptionPimodivir
- Packaging5mg
- Price$93
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-6423
- Product descriptionPimodivir 99.45%
- Packaging5mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6423
- Product descriptionPimodivir 99.45%
- Packaging10mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6423
- Product descriptionPimodivir 99.45%
- Packaging25mg
- Price$270
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9815
- Product descriptionPimodivir(VX-787） >98%
- Packaging1g
- Price$2700
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberP447815
- Product descriptionPimodivir
- Packaging10mg
- Price$140
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | API-1946 | VX787 VX787 | 1g | $2300 | 2021-12-16 | Buy |
| Cayman Chemical | 29321 | Pimodivir | 25mg | $343 | 2024-03-01 | Buy |
| Cayman Chemical | 29321 | Pimodivir | 10mg | $146 | 2024-03-01 | Buy |
| Cayman Chemical | 29321 | Pimodivir | 5mg | $93 | 2024-03-01 | Buy |
| ChemScene | CS-6423 | Pimodivir 99.45% | 5mg | $90 | 2021-12-16 | Buy |
| ChemScene | CS-6423 | Pimodivir 99.45% | 10mg | $150 | 2021-12-16 | Buy |
| ChemScene | CS-6423 | Pimodivir 99.45% | 25mg | $270 | 2021-12-16 | Buy |
| DC Chemicals | DC9815 | Pimodivir(VX-787） >98% | 1g | $2700 | 2021-12-16 | Buy |
| TRC | P447815 | Pimodivir | 10mg | $140 | 2021-12-16 | Buy |
Properties
Density :1.501±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO, not in water:100.0(Max Conc. mg/mL);250.38(Max Conc. mM)
form :A solid
pka :4.32±0.40(Predicted)
color :White to light yellow
storage temp. :Store at -20°C
solubility :Soluble in DMSO, not in water:100.0(Max Conc. mg/mL);250.38(Max Conc. mM)
form :A solid
pka :4.32±0.40(Predicted)
color :White to light yellow
Safety Information
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Description
Pimodivir is an inhibitor of influenza virus polymerase basic protein 2 (PB2; KD = <0.003 μM). It also binds to glycogen synthase kinase 3β (GSK3β; Ki = ~1.6 μM) and inhibits the activity of Axl and calcium/calmodulin-dependent protein kinase IIβ (CaMKIIβ) by greater than 50% in a panel of 65 human and rat kinases. Pimodivir decreases the replication of seven adamantine- and neuraminidase inhibitor-resistant strains of influenza virus A (EC50s = <0.15-2.8 nM in a cell-based assay). It increases the antiviral activity of oseltamivir , zanamivir , and favipiravir (T-705; ) with 50% combination index (CI50) values of 0.58, 0.64, and 0.89, respectively, in a cell-based assay. Pimodivir increases survival in a mouse model of intranasal influenza A infection when administered at doses of 1, 3, and 10 mg/kg twice per day.Related product price
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