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ChemicalBook >> CAS DataBase List >> Pagoclone

Pagoclone

Pagoclone price.
  • $50 - $1680
  • Product name: Pagoclone
  • CAS: 133737-48-1
  • MF: C23H22ClN3O2
  • MW: 407.89
  • EINECS:
  • MDL Number:MFCD00864700
  • Synonyms:PAGOCLONE;1H-Isoindol-1-one, 2-(7-chloro-1,8-naphthyridin-2-yl)-2,3-dihydro-3-(5-methyl-2-oxohexyl)-;2-(7-Chloro-2-naphthyridin-1,8-yl)-3-(5-methyl-2-oxohexyl)isoindolin-1-one;Pagoclone Labeled d4;2-(7-chloro-1,8-naphthyridine-2-yl)-3-(5-methyl-2-oxo-hexyl)-1-isoindolinone;rac-Pagoclone
7 prices
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Brand
  • Chemtos
  • Crysdot
  • TRC
Package
  • 1mg
  • 10mg
  • 25mg
  • 50mg
  • 250mg
  • ManufacturerChemtos
  • Product numberP-2470
  • Product descriptionPagocloneLabeledd4
  • Packaging25mg
  • Price$1680
  • Updated2021-12-16
  • Buy
  • ManufacturerChemtos
  • Product numberP-2470
  • Product descriptionPagocloneLabeledd4
  • Packaging50mg
  • Price$1680
  • Updated2021-12-16
  • Buy
  • ManufacturerChemtos
  • Product numberP-2470
  • Product descriptionPagocloneLabeledd4
  • Packaging10mg
  • Price$1680
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11292281
  • Product description2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)isoindolin-1-one 97%
  • Packaging250mg
  • Price$1191
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11292281
  • Product description2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)isoindolin-1-one 97%
  • Packaging50mg
  • Price$396
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberP133845
  • Product descriptionrac-Pagoclone
  • Packaging1mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberP133845
  • Product descriptionrac-Pagoclone
  • Packaging25mg
  • Price$400
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Chemtos P-2470 PagocloneLabeledd4 25mg $1680 2021-12-16 Buy
Chemtos P-2470 PagocloneLabeledd4 50mg $1680 2021-12-16 Buy
Chemtos P-2470 PagocloneLabeledd4 10mg $1680 2021-12-16 Buy
Crysdot CD11292281 2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)isoindolin-1-one 97% 250mg $1191 2021-12-16 Buy
Crysdot CD11292281 2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)isoindolin-1-one 97% 50mg $396 2021-12-16 Buy
TRC P133845 rac-Pagoclone 1mg $50 2021-12-16 Buy
TRC P133845 rac-Pagoclone 25mg $400 2021-12-16 Buy

Properties

Melting point :173-179°C
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
color :Pale Orange to Pale Red

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Pagoclone is a new cyclopyrrolone partial agonist. In animal models of antianxiety activity, pagoclone is more potent than benzodiazepines, is less sedating, and has a high therapeutic index (Table 29–1). In clinical studies, pagoclone is well tolerated and does not appear to cause sedation or affect psychomotor or cognitive performance. In studies of volunteers, it has been shown that it does not cause withdrawal symptoms on abrupt discontinuation after 14 days. These factors all suggest that pagoclone may be an important drug for the future. It is currently entering dose-ranging and comparative studies involving patients with anxiety disorders, and in a pilot crossover study, it reduced panic attacks; adverse effects were not different from or more numerous than those reported with placebo (Sandford et al. 1998).