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ChemicalBook >> CAS DataBase List >> Oxaliplatin

Oxaliplatin

Oxaliplatin price.
  • $19 - $2240
  • Product name: Oxaliplatin
  • CAS: 61825-94-3
  • MF: C8H12N2O4Pt
  • MW: 395.28
  • EINECS:621-248-1
  • MDL Number:MFCD00866327
  • Synonyms:[SP-4-2-(1R-TRANS)]-(1,2-CYCLOHEXANEDIAMINE-N,N')[ETHANEDIOATA(2-)-O,O']PLATINUM;OXALIPLATIN;trans-l-diaminocyclohexane oxalatoplatinum;(1,2-cyclohexanediamine-n,n’)(ethanedioato(2-)-o,o’)-platinu(sp-4-2-(1r-tr ;oxalato(1r,2r-cyclohexanediammine)platinum(ii) ;oxalatoplatin ;[SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N,)[ethanedioato(2-)-O,O’Jplatinum;NSC-266046:Elocatin
49 prices
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Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Alfa Aesar
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • BroadPharm
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • JR MediChem
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
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  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3592-M005
  • Product descriptionOxaliplatin ≥98%(1H-NMR)
  • Packaging5mg
  • Price$20
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ50808
  • Product descriptionOxaliplatin
  • Packaging10g
  • Price$795
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberH874
  • Product descriptionOxaliplatin
  • Packaging25g
  • Price$2107
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ66586
  • Product descriptionOxaliplatin
  • Packaging50mg
  • Price$168
  • Updated2023-06-20
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8648
  • Product descriptionOxaliplatin
  • Packaging200mg
  • Price$145
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS027937
  • Product descriptionOxalato(trans-l-1,2-cyclohexanediamine)platinum(II) ≥98%
  • Packaging50mg
  • Price$19
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS027937
  • Product descriptionOxalato(trans-l-1,2-cyclohexanediamine)platinum(II) ≥98%
  • Packaging100mg
  • Price$31
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS027937
  • Product descriptionOxalato(trans-l-1,2-cyclohexanediamine)platinum(II) ≥98%
  • Packaging250mg
  • Price$38
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS027937
  • Product descriptionOxalato(trans-l-1,2-cyclohexanediamine)platinum(II) ≥98%
  • Packaging1g
  • Price$129
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS027937
  • Product descriptionOxalato(trans-l-1,2-cyclohexanediamine)platinum(II) ≥98%
  • Packaging5g
  • Price$534
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS027937
  • Product descriptionOxalato(trans-l-1,2-cyclohexanediamine)platinum(II) ≥98%
  • Packaging25g
  • Price$1960
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1511
  • Product descriptionOxaliplatin
  • Packaging5g
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1511
  • Product descriptionOxaliplatin
  • Packaging1g
  • Price$145
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1511
  • Product descriptionOxaliplatin
  • Packaging100mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb61070
  • Product descriptionOxaliplatin >99% pure
  • Packaging300mg
  • Price$360.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb61070
  • Product descriptionOxaliplatin >99% pure
  • Packaging500mg
  • Price$472.6
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-3592-M005 Oxaliplatin ≥98%(1H-NMR) 5mg $20 2021-12-16 Buy
AK Scientific J50808 Oxaliplatin 10g $795 2021-12-16 Buy
AK Scientific H874 Oxaliplatin 25g $2107 2021-12-16 Buy
Alfa Aesar J66586 Oxaliplatin 50mg $168 2023-06-20 Buy
ApexBio Technology A8648 Oxaliplatin 200mg $145 2021-12-16 Buy
Arctom AS027937 Oxalato(trans-l-1,2-cyclohexanediamine)platinum(II) ≥98% 50mg $19 2021-12-16 Buy
Arctom AS027937 Oxalato(trans-l-1,2-cyclohexanediamine)platinum(II) ≥98% 100mg $31 2021-12-16 Buy
Arctom AS027937 Oxalato(trans-l-1,2-cyclohexanediamine)platinum(II) ≥98% 250mg $38 2021-12-16 Buy
Arctom AS027937 Oxalato(trans-l-1,2-cyclohexanediamine)platinum(II) ≥98% 1g $129 2021-12-16 Buy
Arctom AS027937 Oxalato(trans-l-1,2-cyclohexanediamine)platinum(II) ≥98% 5g $534 2021-12-16 Buy
Arctom AS027937 Oxalato(trans-l-1,2-cyclohexanediamine)platinum(II) ≥98% 25g $1960 2021-12-16 Buy
AvaChem 1511 Oxaliplatin 5g $450 2021-12-16 Buy
AvaChem 1511 Oxaliplatin 1g $145 2021-12-16 Buy
AvaChem 1511 Oxaliplatin 100mg $65 2021-12-16 Buy
Biorbyt Ltd orb61070 Oxaliplatin >99% pure 300mg $360.4 2021-12-16 Buy
Biorbyt Ltd orb61070 Oxaliplatin >99% pure 500mg $472.6 2021-12-16 Buy

Properties

alpha :+74.5-78.0 (D/20)(c=0.5,H2O)
storage temp. :2-8°C
solubility :Slightly soluble in water, very slightly soluble in methanol, practically insoluble in anhydrous ethanol.
form :solid
color :White to Almost white
Water Solubility :Soluble in water with heating and/or sonication
Merck :14,6912
Stability :Stable. Store cool. Incompatible with oxidizing agents.
InChI :InChI=1/C6H12N2.C2H2O4.Pt/c7-5-3-1-2-4-6(5)8;3-1(4)2(5)6;/h5-8H,1-4H2;(H,3,4)(H,5,6);/q-2;;+4/p-2/t5-,6-;;/s3
InChIKey :ZROHGHOFXNOHSO-BNTLRKBRSA-L
SMILES :O=C1C([O-][Pt+2]2(N[C@]3([H])CCCC[C@@]3([H])N2)[O-]1)=O |&1:6,12,r|
CAS DataBase Reference :61825-94-3

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H340 May cause genetic defects Germ cell mutagenicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Oxaliplatin is a platinum-based antineoplastic agent that functions by forming DNA adducts specifically in cancer cells, preventing DNA replication and transcription which leads to cell death. Oxaliplatin has cytotoxic effects in a broad range of cell lines, including colon, ovarian, and lung cancer, with IC50 values ranging from 0.5-240, 0.12-19.8, and 2.6-6.1 μM, respectively. Through its general cytotoxic effects, oxaliplatin has anti-tumor activity against advanced colorectal cancer and is typically administered with fluorouracil and leucovorin in a combination known as FOLFOX.

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