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ChemicalBook >> CAS DataBase List >> ODM-201

ODM-201

ODM-201 price.
  • $44 - $16560
  • Product name: ODM-201
  • CAS: 1297538-32-9
  • MF: C19H19ClN6O2
  • MW: 398.85
  • EINECS:829-313-8
  • MDL Number:MFCD29472270
  • Synonyms:ODM-201;N-[(1S)-2-[3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethyl]-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide;N-((S)-1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide;Darolutamide (ODM-201);ODM-201(BAY-1841788);CS-1565;ODM-201(Darolutamide);N-{(2S)-1-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]propan-2-yl}-5-[(1RS)-1-hydroxyethyl]-1H-pyrazole-3-carboxamide
26 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 10mM(in 1mL DMSO)
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 100g
  • ManufacturerAK Scientific
  • Product number3179DT
  • Product descriptionDarolutamide
  • Packaging10mg
  • Price$218
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA147162
  • Product descriptionN-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide 98+%
  • Packaging2mg
  • Price$53
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA147162
  • Product descriptionN-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide 98+%
  • Packaging5mg
  • Price$69
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA147162
  • Product descriptionN-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide 98+%
  • Packaging10mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA147162
  • Product descriptionN-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide 98+%
  • Packaging25mg
  • Price$117
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA147162
  • Product descriptionN-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide 98+%
  • Packaging50mg
  • Price$152
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA147162
  • Product descriptionN-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide 98+%
  • Packaging100mg
  • Price$197
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA147162
  • Product descriptionN-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide 98+%
  • Packaging250mg
  • Price$295
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA147162
  • Product descriptionN-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide 98+%
  • Packaging1g
  • Price$739
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8452
  • Product descriptionODM-201
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8452
  • Product descriptionODM-201
  • Packaging10mM(in 1mL DMSO)
  • Price$132
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8452
  • Product descriptionODM-201
  • Packaging10mg
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8452
  • Product descriptionODM-201
  • Packaging50mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD161413
  • Product descriptionDarolutamide
  • Packaging10mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD161413
  • Product descriptionDarolutamide
  • Packaging50mg
  • Price$437.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number25643
  • Product descriptionODM-201 ≥98%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3179DT Darolutamide 10mg $218 2021-12-16 Buy
Ambeed A147162 N-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide 98+% 2mg $53 2021-12-16 Buy
Ambeed A147162 N-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide 98+% 5mg $69 2021-12-16 Buy
Ambeed A147162 N-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide 98+% 10mg $90 2021-12-16 Buy
Ambeed A147162 N-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide 98+% 25mg $117 2021-12-16 Buy
Ambeed A147162 N-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide 98+% 50mg $152 2021-12-16 Buy
Ambeed A147162 N-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide 98+% 100mg $197 2021-12-16 Buy
Ambeed A147162 N-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide 98+% 250mg $295 2021-12-16 Buy
Ambeed A147162 N-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide 98+% 1g $739 2021-12-16 Buy
ApexBio Technology A8452 ODM-201 5mg $120 2021-12-16 Buy
ApexBio Technology A8452 ODM-201 10mM(in 1mL DMSO) $132 2021-12-16 Buy
ApexBio Technology A8452 ODM-201 10mg $190 2021-12-16 Buy
ApexBio Technology A8452 ODM-201 50mg $450 2021-12-16 Buy
Biosynth Carbosynth FD161413 Darolutamide 10mg $125 2021-12-16 Buy
Biosynth Carbosynth FD161413 Darolutamide 50mg $437.5 2021-12-16 Buy
Cayman Chemical 25643 ODM-201 ≥98% 1mg $44 2024-03-01 Buy

Properties

Melting point :169 - 171°C
Boiling point :719.5±60.0 °C(Predicted)
Density :1.41±0.1 g/cm3(Predicted)
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly)
pka :11.10±0.10(Predicted)
form :Solid
color :White to Off-White

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P391 Collect spillage. Hazardous to the aquatic environment
P501 Dispose of contents/container to..…

Description

ODM-201 is a novel androgen receptor (AR) inhibit designed to inhibit the growth of prostate cancer cells through binding to the AR to inhibit the  testosterone-induced AR nuclear translocation. It is particularly used in patients with progressive metastatic castration-resistant prostate cancer. It is effective in inhibiting the activity of some mutant ARs emerging during antiandrogen therapies, including the F876L mutation version which is resistant to enzalutamide and ARN-509 (the second-generation antiandrogens).Therefore, it has potential to overcome the resistance issue occurring upon AR-targeted therapies.

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