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ChemicalBook >> CAS DataBase List >> Novobiocin

Novobiocin

Novobiocin price.
  • $90 - $1706.75
  • Product name: Novobiocin
  • CAS: 303-81-1
  • MF: C31H36N2O11
  • MW: 612.62
  • EINECS:206-146-3
  • MDL Number:
  • Synonyms:NOVOBIOCIN;cathocin ;cathomycin ;crystallinicacid ;-hexopyranosyl)oxy)-4-hydroxy-8-methyl-2-oxo-2h-1-benzopyran-3-yl)-4-hydroxy- ;novo-r ;pa93 ;U 6391
8 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 1MG
  • 5MG
  • 25mg
  • 100mg
  • 500mg
  • ManufacturerAK Scientific
  • Product number9542BB
  • Product descriptionNovobiocin
  • Packaging25mg
  • Price$239
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0009006
  • Product descriptionNOVOBIOCIN 90.00%
  • Packaging5MG
  • Price$1706.75
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0009006
  • Product descriptionNOVOBIOCIN 90.00%
  • Packaging1MG
  • Price$997.5
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberPH003623
  • Product description(3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-3-(3-methylbut-2-enyl)benzamido)-8-methyl-2-oxo-2H-chromen-7-yloxy)-3-methoxy-2,2-dimethyltetrahydro-2H-pyran-4-yl carbamate AldrichCPR
  • Packaging1MG
  • Price$172
  • Updated2023-06-20
  • Buy
  • ManufacturerTRC
  • Product numberN825320
  • Product descriptionNovobiocin
  • Packaging25mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberN825320
  • Product descriptionNovobiocin
  • Packaging100mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberN825320
  • Product descriptionNovobiocin
  • Packaging500mg
  • Price$805
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product numberN5376-61
  • Product descriptionNovobiocin
  • Packaging5mg
  • Price$362
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9542BB Novobiocin 25mg $239 2021-12-16 Buy
American Custom Chemicals Corporation API0009006 NOVOBIOCIN 90.00% 5MG $1706.75 2021-12-16 Buy
American Custom Chemicals Corporation API0009006 NOVOBIOCIN 90.00% 1MG $997.5 2021-12-16 Buy
Sigma-Aldrich PH003623 (3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-3-(3-methylbut-2-enyl)benzamido)-8-methyl-2-oxo-2H-chromen-7-yloxy)-3-methoxy-2,2-dimethyltetrahydro-2H-pyran-4-yl carbamate AldrichCPR 1MG $172 2023-06-20 Buy
TRC N825320 Novobiocin 25mg $90 2021-12-16 Buy
TRC N825320 Novobiocin 100mg $180 2021-12-16 Buy
TRC N825320 Novobiocin 500mg $805 2021-12-16 Buy
Usbiological N5376-61 Novobiocin 5mg $362 2021-12-16 Buy

Properties

Melting point :170-172 °C
alpha :D24 -63.0° (c = 1 in ethanol)
Boiling point :657.29°C (rough estimate)
Density :1.3448
refractive index :1.5800 (estimate)
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :pKa1 4.3; pKa2 9.1(at 25℃)
color :White to Pale Yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Novobiocin (Albamycin, Cathamycin, Spheromycin) is an aminocoumarin antibiotic originally isolated from Streptomyces niveus in the Upjohn Research Laboratories and initially was given the generic name of ‘streptonivicin’ . It was also isolated almost simultaneously in other laboratories, and was given several other names. Novobiocin inhibits the GyrB subunit of DNA gyrase and is primarily active against Gram-positive microorganisms. It was used under the trade name Albamycin and was withdrawn from the market in the US. Its latest use included eradication of methicillin-resistant Staphylococcus aureus (MRSA) and other resistant microorganisms. In addition, it has been applied in cancer therapy.

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