Notoginsenoside Ft1
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- $26 - $1069.3
- Product name: Notoginsenoside Ft1
- CAS: 155683-00-4
- MF: C47H80O17
- MW: 917.13
- EINECS:
- MDL Number:MFCD22125013
- Synonyms:Notoginsenoside Ft1;(3beta,12beta,20R)-12,20-Dihydroxydammar-24-en-3-yl O-beta-D-xylopyranosyl-(1- 2)-O-beta-D-glucopyranosyl-(1-2)-beta-D-glucopyranoside;product/153944;β-D-Glucopyranoside, (3β,12β,20R)-12,20-dihydroxydammar-24-en-3-yl O-β-D-xylopyranosyl-(1→2)-O-β-D-glucopyranosyl-(1→2)-;(2S,3R,4S,5R)-2-[(2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-17-[(2R)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol
17 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- AvaChem
- Biorbyt Ltd
- Cayman Chemical
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
Package
- 500μg
- 1mg
- 5mg
- 10mg
- 20mg
- 25mg
- 50mg
- 100mg
- ManufacturerAK Scientific
- Product number8189AH
- Product descriptionNotoginsenosideFT1
- Packaging5mg
- Price$413
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number8189AH
- Product descriptionNotoginsenosideFT1
- Packaging10mg
- Price$608
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN2245
- Product descriptionNotoginsenosideFt1
- Packaging20mg
- Price$400
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2929
- Product descriptionNotoginsenoside Ft1
- Packaging5mg
- Price$490
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb594406
- Product descriptionNotoginsenoside Ft1
- Packaging20mg
- Price$499.8
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb594406
- Product descriptionNotoginsenoside Ft1
- Packaging100mg
- Price$1069.3
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb105495
- Product descriptionNotoginsenoside Ft1 >98%,Standard References Grade
- Packaging20mg
- Price$569.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number24976
- Product descriptionNotoginsenoside Ft1 ≥95%
- Packaging10mg
- Price$102
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number24976
- Product descriptionNotoginsenoside Ft1 ≥95%
- Packaging5mg
- Price$83
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number24976
- Product descriptionNotoginsenoside Ft1 ≥95%
- Packaging500μg
- Price$32
- Updated2023-01-06
- Buy
- ManufacturerCayman Chemical
- Product number24976
- Product descriptionNotoginsenoside Ft1 ≥95%
- Packaging1mg
- Price$26
- Updated2024-03-01
- Buy
- ManufacturerCrysdot
- Product numberCD32002316
- Product descriptionNotoginsenosideFt1 98+%
- Packaging10mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD32002316
- Product descriptionNotoginsenosideFt1 98+%
- Packaging25mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD32002316
- Product descriptionNotoginsenosideFt1 98+%
- Packaging50mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD32002316
- Product descriptionNotoginsenosideFt1 98+%
- Packaging100mg
- Price$440
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDCS-084
- Product descriptionNotoginsenosideFt1 >98%,StandardReferencesGrade
- Packaging20mg
- Price$280
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 8189AH | NotoginsenosideFT1 | 5mg | $413 | 2021-12-16 | Buy |
| AK Scientific | 8189AH | NotoginsenosideFT1 | 10mg | $608 | 2021-12-16 | Buy |
| ApexBio Technology | N2245 | NotoginsenosideFt1 | 20mg | $400 | 2021-12-16 | Buy |
| AvaChem | 2929 | Notoginsenoside Ft1 | 5mg | $490 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb594406 | Notoginsenoside Ft1 | 20mg | $499.8 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb594406 | Notoginsenoside Ft1 | 100mg | $1069.3 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb105495 | Notoginsenoside Ft1 >98%,Standard References Grade | 20mg | $569.5 | 2021-12-16 | Buy |
| Cayman Chemical | 24976 | Notoginsenoside Ft1 ≥95% | 10mg | $102 | 2024-03-01 | Buy |
| Cayman Chemical | 24976 | Notoginsenoside Ft1 ≥95% | 5mg | $83 | 2024-03-01 | Buy |
| Cayman Chemical | 24976 | Notoginsenoside Ft1 ≥95% | 500μg | $32 | 2023-01-06 | Buy |
| Cayman Chemical | 24976 | Notoginsenoside Ft1 ≥95% | 1mg | $26 | 2024-03-01 | Buy |
| Crysdot | CD32002316 | NotoginsenosideFt1 98+% | 10mg | $70 | 2021-12-16 | Buy |
| Crysdot | CD32002316 | NotoginsenosideFt1 98+% | 25mg | $140 | 2021-12-16 | Buy |
| Crysdot | CD32002316 | NotoginsenosideFt1 98+% | 50mg | $250 | 2021-12-16 | Buy |
| Crysdot | CD32002316 | NotoginsenosideFt1 98+% | 100mg | $440 | 2021-12-16 | Buy |
| DC Chemicals | DCS-084 | NotoginsenosideFt1 >98%,StandardReferencesGrade | 20mg | $280 | 2021-12-16 | Buy |
Properties
Boiling point :997.8±65.0 °C(Predicted)
Density :1.36±0.1 g/cm3(Predicted)
solubility :DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 15 mg/ml; Ethanol: 5 mg/ml
form :A crystalline solid
pka :12.84±0.70(Predicted)
color :White to off-white
Density :1.36±0.1 g/cm3(Predicted)
solubility :DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 15 mg/ml; Ethanol: 5 mg/ml
form :A crystalline solid
pka :12.84±0.70(Predicted)
color :White to off-white
Safety Information
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Description
Notoginsenoside Ft1 is a saponin originally isolated from P. notoginseng with diverse biological activities. It induces proliferation, migration, and tube formation of human umbilical vein endothelial cells (HUVECs) via nuclear translocation of hypoxia-inducible factor-1α (HIF-1α) and activation of the PI3K/AKT and Raf/MEK/ERK signaling pathways in a manner dependent on mammalian target of rapamycin (mTOR). Notoginsenoside Ft1 (45 μM) induces cell cycle arrest at the S and G2/M phases and promotes apoptosis of SH-SY5Y cells. It increases cGMP levels and induces relaxation of isolated precontracted rat mesenteric arteries, effects that are reversed by the nitric oxide synthase inhibitor L-NAME and ODQ , an inhibitor of soluble guanylyl cyclase. In vivo, notoginsenoside Ft1 (0.25, 2.5, and 25 mg/kg) promotes angiogenesis and decreases wound diameter in a mouse model of punched-hole ear injury. Notoginsenoside Ft1 (1.25 mg/kg) decreases tail bleeding time and increases thrombus weight in a rat tail bleeding assay. Topical administration of notoginsenoside Ft1 increases mRNA expression of the collagen expression, fibroblast proliferation, and scar formation genes COL1A1, COL3A1, TGF-β1, TGF-β3, and fibronectin, promotes neovascularization, reduces monocyte infiltration, and shortens wound closure time in a db/db mouse model of diabetic foot ulcers.More related product prices
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