Methylene boldenone
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- $263 - $2280
- Product name: Methylene boldenone
- CAS: 122370-91-6
- MF: C20H26O2
- MW: 298.42
- EINECS:
- MDL Number:
- Synonyms:METHYLENE BOLDENONE;(17b)-17-Hydroxy-6-methyleneandrosta-1,4-dien-3-one;(17)-17-Hydroxy-6-methyleneandrosta-1,4-dien-3-one;17--Hydroxy Exemestane;(17β)-;17β-Hydroxy ExeMestane SulfaMate;Exemestane 17β-Hydroxy Impurity;Androsta-1,4-dien-3-one, 17-hydroxy-6-methylene-, (17β)-
7 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
- Medical Isotopes, Inc.
- TRC
Package
- 1mg
- 5mg
- 10mg
- ManufacturerAK Scientific
- Product number7621CS
- Product descriptionMethyleneBoldenone,
- Packaging1mg
- Price$390
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number7621CS
- Product descriptionMethyleneBoldenone,
- Packaging5mg
- Price$1043
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0005601
- Product description17BETA-HYDROXY EXEMESTANE 95.00%
- Packaging5MG
- Price$497.27
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number27989
- Product description17β-hydroxy Exemestane
- Packaging5mg
- Price$848
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27989
- Product description17β-hydroxy Exemestane
- Packaging1mg
- Price$263
- Updated2024-03-01
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number70677
- Product description17β-HydroxyExemestaneSulfamate
- Packaging10mg
- Price$2280
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberH942345
- Product description17β-HydroxyExemestaneSulfamate
- Packaging10mg
- Price$1410
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 7621CS | MethyleneBoldenone, | 1mg | $390 | 2021-12-16 | Buy |
| AK Scientific | 7621CS | MethyleneBoldenone, | 5mg | $1043 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0005601 | 17BETA-HYDROXY EXEMESTANE 95.00% | 5MG | $497.27 | 2021-12-16 | Buy |
| Cayman Chemical | 27989 | 17β-hydroxy Exemestane | 5mg | $848 | 2024-03-01 | Buy |
| Cayman Chemical | 27989 | 17β-hydroxy Exemestane | 1mg | $263 | 2024-03-01 | Buy |
| Medical Isotopes, Inc. | 70677 | 17β-HydroxyExemestaneSulfamate | 10mg | $2280 | 2021-12-16 | Buy |
| TRC | H942345 | 17β-HydroxyExemestaneSulfamate | 10mg | $1410 | 2021-12-16 | Buy |
Properties
Melting point :134-136°C
Density :1.14
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Solid
color :Off-White
CAS DataBase Reference :122370-91-6
Density :1.14
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Solid
color :Off-White
CAS DataBase Reference :122370-91-6
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Warning | |||||||||||||||||||||
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Description
17β-hydroxy Exemestane is the primary active metabolite of exemestane . It is formed by metabolism of exemestane by the cytochrome P450 (CYP) isoforms CYP1A and CYP4A11. 17β-hydroxy Exemestane is an aromatase inhibitor (IC50 = 69 nM using human placental microsomes) and an androgen receptor (AR) agonist (IC50 = 39.6 nM) that is selective for AR over estrogen receptor α (ERα; IC50 = 21.2 μM). It stimulates growth of AR- and ERα-positive MCF-7 (EC50 = 2.7 μM) and T47D breast cancer cells (EC50s = 0.43 and 1,500 nM for AR- and ER-mediated growth, respectively) and inhibits proliferation of testosterone-treated aromatase-overexpressing MCF-7aro cells in a concentration-dependent manner. 17β-hydroxy Exemestane (20 mg/kg) inhibits increases in serum cholesterol and LDL levels and prevents decreases in bone mineral density in the lumbar vertebrae and femur, as well as femoral bending strength and compressive strength of the fifth lumbar vertebrae, in ovariectomized rats.Related product price
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Suppliers and manufacturers
Hubei Jusheng Technology Co.,Ltd.
CONIER CHEM AND PHARMA LIMITED
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SUZHOU SENFEIDA CHEMICAL CO.,LTD
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QUALITY CONTROL SOLUTIONS LTD.
J & K SCIENTIFIC LTD.
Chemsky（shanghai）International Co.,Ltd.
Clearsynth Labs Limited
Cato Research Chemicals Inc.