MLN9708
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- $28 - $10065.83
- Product name: MLN9708
- CAS: 1201902-80-8
- MF: C20H23BCl2N2O9
- MW: 517.12
- EINECS:-0
- MDL Number:MFCD18251437
- Synonyms:4-(carboxymethyl)-2-((R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)-6-oxo-1,3,2-dioxaborinane-4-carboxylic acid;MLN9708;MLN9708,MLN-9708,MLN 9708;4-Carboxy-2-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]-6-oxo-1,3,2-dioxaborinane-4-acetic acid;4-Carboxy-2-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]-6-oxo-1,3,2-dioxaborinane-4-acetic acid MLN9708;Ixazomib Citrate;MLN9708;MLN-9708;4-(Carboxymethyl)-2-((R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)-6-oxo-1,3,2-dio
18 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Ark Pharm
- Axon Medchem
- Cayman Chemical
- Crysdot
- TRC
Package
- 1unit
- 1mg
- 2mg
- 5mg
- 10MG
- 2x5mg
- 20mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1G
- ManufacturerAK Scientific
- Product numberX7548
- Product descriptionMLN9708
- Packaging5mg
- Price$170
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX7548
- Product descriptionMLN9708
- Packaging250mg
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000901
- Product descriptionMLN-9708 95.00%
- Packaging10MG
- Price$1006.58
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000901
- Product descriptionMLN-9708 95.00%
- Packaging1G
- Price$10065.83
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4007
- Product descriptionMLN9708
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60408
- Product descriptionIxazomibCitrate(MLN9708)
- Packaging20mg
- Price$258
- Updated2021-12-16
- Buy
- ManufacturerArk Pharm
- Product numberP000022748
- Product descriptionIxazomib citrate 98+%
- Packaging2mg
- Price$96
- Updated2021-12-16
- Buy
- ManufacturerArk Pharm
- Product numberP000022748
- Product descriptionIxazomib citrate 98+%
- Packaging5mg
- Price$144
- Updated2021-12-16
- Buy
- ManufacturerArk Pharm
- Product numberP000022748
- Product descriptionIxazomib citrate 98+%
- Packaging10mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerArk Pharm
- Product numberP000022748
- Product descriptionIxazomib citrate 98+%
- Packaging50mg
- Price$654
- Updated2021-12-16
- Buy
- ManufacturerArk Pharm
- Product numberP000022748
- Product descriptionIxazomib citrate 98+%
- Packaging100mg
- Price$916
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2557
- Product descriptionMLN9708-Ixazomibcitrate 99%
- Packaging2x5mg
- Price$165
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18386
- Product descriptionMLN9708 ≥95%
- Packaging1mg
- Price$43
- Updated2023-06-20
- Buy
- ManufacturerCayman Chemical
- Product number18386
- Product descriptionMLN9708 ≥95%
- Packaging5mg
- Price$60
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18386
- Product descriptionMLN9708 ≥95%
- Packaging10mg
- Price$89
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18386
- Product descriptionMLN9708 ≥95%
- Packaging50mg
- Price$208
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | X7548 | MLN9708 | 5mg | $170 | 2021-12-16 | Buy |
| AK Scientific | X7548 | MLN9708 | 250mg | $420 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000901 | MLN-9708 95.00% | 10MG | $1006.58 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000901 | MLN-9708 95.00% | 1G | $10065.83 | 2021-12-16 | Buy |
| ApexBio Technology | A4007 | MLN9708 | 1unit | $28 | 2021-12-16 | Buy |
| Arctom | CFN60408 | IxazomibCitrate(MLN9708) | 20mg | $258 | 2021-12-16 | Buy |
| Ark Pharm | P000022748 | Ixazomib citrate 98+% | 2mg | $96 | 2021-12-16 | Buy |
| Ark Pharm | P000022748 | Ixazomib citrate 98+% | 5mg | $144 | 2021-12-16 | Buy |
| Ark Pharm | P000022748 | Ixazomib citrate 98+% | 10mg | $218 | 2021-12-16 | Buy |
| Ark Pharm | P000022748 | Ixazomib citrate 98+% | 50mg | $654 | 2021-12-16 | Buy |
| Ark Pharm | P000022748 | Ixazomib citrate 98+% | 100mg | $916 | 2021-12-16 | Buy |
| Axon Medchem | Axon2557 | MLN9708-Ixazomibcitrate 99% | 2x5mg | $165 | 2021-12-16 | Buy |
| Cayman Chemical | 18386 | MLN9708 ≥95% | 1mg | $43 | 2023-06-20 | Buy |
| Cayman Chemical | 18386 | MLN9708 ≥95% | 5mg | $60 | 2024-03-01 | Buy |
| Cayman Chemical | 18386 | MLN9708 ≥95% | 10mg | $89 | 2024-03-01 | Buy |
| Cayman Chemical | 18386 | MLN9708 ≥95% | 50mg | $208 | 2024-03-01 | Buy |
Properties
Melting point :>227°C (dec.)
Density :1.47
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
pka :1.92±0.20(Predicted)
form :Solid
color :White to Off-White
Density :1.47
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
pka :1.92±0.20(Predicted)
form :Solid
color :White to Off-White
Safety Information
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Description
MLN9708 is an orally bioavailable prodrug of the second-generation proteasome inhibitor MLN2239 . This prodrug rapidly hydrolyzes in plasma to the biologically active form, which inhibits the β5 chymotryptic-like subunit of the 20S proteasome (IC50 = 3.4 nM; Ki = 0.93 nM in cell-free assays). It inhibits the β1 caspase-like and β2 trypsin-like proteolytic sites with IC50 values of 0.03 and 3.5 μM, respectively. MLN9708 has shown antitumor activity both in cell-based assays and in xenograft models and has been examined in phase III clinical trials for potential antimyeloma activity.More related product prices
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