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ChemicalBook >> CAS DataBase List >> M344

M344

M344 price.
  • $26 - $1800
  • Product name: M344
  • CAS: 251456-60-7
  • MF: C16H25N3O3
  • MW: 307.39
  • EINECS:
  • MDL Number:MFCD03453554
  • Synonyms:M344;HISTONE DEACETYLASE INHIBITOR III;4-DIMETHYLAMINO-N-(6-HYDROXYCARBAMOYLHEXYL)-BENZAMIDE;N-HYDROXY-7-(4-DIMETHYLAMINOBENZOYL)AMINOHEPTANAMIDE;4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]-benzamide, MS 344, D237, N-Hydroxy-7-(4-dimethylaminobenzoyl)-aminoheptanamide;4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]-benzamide;MS 344;M 344 (enzyme inhibitor)
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Brand
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 1
  • 1mg
  • 5mg
  • 10mg
  • 20MG
  • 10
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product number3802AH
  • Product description4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
  • Packaging5mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3802AH
  • Product description4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
  • Packaging10mg
  • Price$182
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ64940
  • Product descriptionHistone Deacetylase Inhibitor III
  • Packaging5mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ64940
  • Product descriptionHistone Deacetylase Inhibitor III
  • Packaging10mg
  • Price$228
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA201295
  • Product description4-(Dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide 98+%
  • Packaging1mg
  • Price$26
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA201295
  • Product description4-(Dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide 98+%
  • Packaging5mg
  • Price$44
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA201295
  • Product description4-(Dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide 98+%
  • Packaging10mg
  • Price$57
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA201295
  • Product description4-(Dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide 98+%
  • Packaging50mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA201295
  • Product description4-(Dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide 98+%
  • Packaging100mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA201295
  • Product description4-(Dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide 98+%
  • Packaging250mg
  • Price$240
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA201295
  • Product description4-(Dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide 98+%
  • Packaging1g
  • Price$599
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000850
  • Product descriptionM344 95.00%
  • Packaging1MG
  • Price$408.6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000850
  • Product descriptionM344 95.00%
  • Packaging5MG
  • Price$443
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000850
  • Product descriptionM344 95.00%
  • Packaging10MG
  • Price$472
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000850
  • Product descriptionM344 95.00%
  • Packaging50MG
  • Price$706
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4105
  • Product descriptionM344
  • Packaging50mg
  • Price$360
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3802AH 4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide 5mg $119 2021-12-16 Buy
AK Scientific 3802AH 4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide 10mg $182 2021-12-16 Buy
Alfa Aesar J64940 Histone Deacetylase Inhibitor III 5mg $119 2021-12-16 Buy
Alfa Aesar J64940 Histone Deacetylase Inhibitor III 10mg $228 2021-12-16 Buy
Ambeed A201295 4-(Dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide 98+% 1mg $26 2021-12-16 Buy
Ambeed A201295 4-(Dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide 98+% 5mg $44 2021-12-16 Buy
Ambeed A201295 4-(Dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide 98+% 10mg $57 2021-12-16 Buy
Ambeed A201295 4-(Dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide 98+% 50mg $96 2021-12-16 Buy
Ambeed A201295 4-(Dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide 98+% 100mg $125 2021-12-16 Buy
Ambeed A201295 4-(Dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide 98+% 250mg $240 2021-12-16 Buy
Ambeed A201295 4-(Dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide 98+% 1g $599 2021-12-16 Buy
American Custom Chemicals Corporation INB0000850 M344 95.00% 1MG $408.6 2021-12-16 Buy
American Custom Chemicals Corporation INB0000850 M344 95.00% 5MG $443 2021-12-16 Buy
American Custom Chemicals Corporation INB0000850 M344 95.00% 10MG $472 2021-12-16 Buy
American Custom Chemicals Corporation INB0000850 M344 95.00% 50MG $706 2021-12-16 Buy
ApexBio Technology A4105 M344 50mg $360 2021-12-16 Buy

Properties

Melting point :161℃
Density :1.137±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :9.48±0.20(Predicted)
form :White solid
color :white to beige
Sensitive :Light Sensitive
CAS DataBase Reference :251456-60-7

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

M 344 is an inhibitor of histone deacetylases (HDACs), inhibiting maize HDAC (IC50 = 100 nM) as well as human HDAC1 (IC50 = 46 nM). It shows a three-fold selectivity for inhibition of HDAC6 over HDAC1. M 344 enhances the sensitivity of human squamous carcinoma cells to radiation and promotes cell cycle arrest and apoptosis in human endometrial cancer and ovarian cancer cells (ED50 = 2.3 μM).

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