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ChemicalBook >> CAS DataBase List >> Fumagillin

Fumagillin

Fumagillin price.
  • $50 - $2800
  • Product name: Fumagillin
  • CAS: 23110-15-8
  • MF: C26H34O7
  • MW: 458.54
  • EINECS:245-433-8
  • MDL Number:MFCD03990453
  • Synonyms:1-oxaspiro(2,5)oct-6-ylester ;2,4,6,8-decatetraenedioicacid,mono[5-methoxy-4-[2-methyl-3-(3-methyl-2-buteny ;5beta,6beta(all-e)]]-theta ;6,8-decatetraenedioicacid,4-(1,2-epoxy-1,5-dimethyl-4-hexenyl)-5-methoxy-4 ;amebacillin ;10-[[5-Methoxy-4-[2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-2-oxaspiro[2.5]oct-6-yl]oxy]-10-oxo-deca-2,4,6,8-tetraenoic acid;Fumagilin DCH;[3R-[3alpha,4alpha(2RX,3RX),5beta,6beta(all-E)]]-2,4,6,8-Decatetraenedioic acid, mono[5-methoxy-4-[2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]oct-6-yl] ester
27 prices
Selected condition：
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Alfa Aesar
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • JR MediChem
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 500μG
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 250mg
  • 1ml
  • 1g
  • 96Tests
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0529-M001
  • Product descriptionFumagillin ≥98%(1H-NMR)
  • Packaging1mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberV0356
  • Product descriptionFumagillin
  • Packaging5mg
  • Price$498
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67045
  • Product descriptionFumagillin, 95%
  • Packaging1mg
  • Price$207
  • Updated2023-06-20
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4407
  • Product descriptionFumagillin
  • Packaging1mg
  • Price$66
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4407
  • Product descriptionFumagillin
  • Packaging5mg
  • Price$230
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545836
  • Product descriptionFumagillin >98%
  • Packaging1mg
  • Price$198.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545836
  • Product descriptionFumagillin >98%
  • Packaging5mg
  • Price$538.9
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11332
  • Product descriptionFumagillin ≥95%
  • Packaging1mg
  • Price$96
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11332
  • Product descriptionFumagillin ≥95%
  • Packaging5mg
  • Price$380
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11332
  • Product descriptionFumagillin ≥95%
  • Packaging10mg
  • Price$680
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2961
  • Product descriptionFumagillin >99.0%
  • Packaging1mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2961
  • Product descriptionFumagillin >99.0%
  • Packaging5mg
  • Price$260
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2961
  • Product descriptionFumagillin >99.0%
  • Packaging10mg
  • Price$480
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2961
  • Product descriptionFumagillin >99.0%
  • Packaging25mg
  • Price$972
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002575
  • Product descriptionFumagillin 98+%
  • Packaging5mg
  • Price$260
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002575
  • Product descriptionFumagillin 98+%
  • Packaging10mg
  • Price$475
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CN2-0529-M001 Fumagillin ≥98%(1H-NMR) 1mg $50 2021-12-16 Buy
AK Scientific V0356 Fumagillin 5mg $498 2021-12-16 Buy
Alfa Aesar J67045 Fumagillin, 95% 1mg $207 2023-06-20 Buy
ApexBio Technology A4407 Fumagillin 1mg $66 2021-12-16 Buy
ApexBio Technology A4407 Fumagillin 5mg $230 2021-12-16 Buy
Biorbyt Ltd orb545836 Fumagillin >98% 1mg $198.9 2021-12-16 Buy
Biorbyt Ltd orb545836 Fumagillin >98% 5mg $538.9 2021-12-16 Buy
Cayman Chemical 11332 Fumagillin ≥95% 1mg $96 2024-03-01 Buy
Cayman Chemical 11332 Fumagillin ≥95% 5mg $380 2024-03-01 Buy
Cayman Chemical 11332 Fumagillin ≥95% 10mg $680 2024-03-01 Buy
ChemScene CS-2961 Fumagillin >99.0% 1mg $60 2021-12-16 Buy
ChemScene CS-2961 Fumagillin >99.0% 5mg $260 2021-12-16 Buy
ChemScene CS-2961 Fumagillin >99.0% 10mg $480 2021-12-16 Buy
ChemScene CS-2961 Fumagillin >99.0% 25mg $972 2021-12-16 Buy
Crysdot CD31002575 Fumagillin 98+% 5mg $260 2021-12-16 Buy
Crysdot CD31002575 Fumagillin 98+% 10mg $475 2021-12-16 Buy

Properties

Melting point :194-195℃
alpha :D25 -26.6° (c = 1 in 95% ethanol)
Boiling point :484.03°C (rough estimate)
Density :1.1368 (rough estimate)
refractive index :1.5800 (estimate)
Flash point :2℃
storage temp. :2-8°C
solubility :ethanol: 1 mg/mL
form :powder
pka :4.27±0.10(Predicted)
color :white
Sensitive :Air Sensitive
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :NGGMYCMLYOUNGM-ZILXAVPASA-N
LogP :3.260 (est)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501 Dispose of contents/container to..…

Description

Fumagillin is an antibiotic derived from the fungus A. fumigatus. It binds and inhibits methionine aminopeptidase-2 with an IC50 value of 10 nM. Fumagillin inhibits angiogenesis by impairing the growth of endothelial cells and altering gene expression. It also impairs microsporidial replication and can be used to treat both conjunctival and intestinal microsporidial infections in immunocompromised patients. Finally, fumagillin reduces diet-induced adipose tissue formation in mice, independent of its effects on angiogenesis.

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