Eplerenone
- $44 - $1732.5
- Product name: Eplerenone
- CAS: 107724-20-9
- MF: C24H30O6
- MW: 414.49
- EINECS:600-850-8
- MDL Number:MFCD05662207
- Synonyms:(2'R,4aS,4bR,5aR,6aS,9aS,9bR,10R)-Methyl 4a,6a-diMethyl-2,4'-dioxo-3,4,4a,4',5a,5',6,6a,8,9,9a,9b,10,11-tetradecahydro-2H,3'H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,2'-furan]-10-carboxylate;HSDB 7522;Pregn-4-ene-7,21-dicarboxylic acid, 9,11-epoxy-17-hydroxy-3-oxo-, gamma-lactone, methyl ester, (7alpha,11alpha,17alpha)-;Eplerenone intermediate Eplerenone;(7α,11α,17α)-9,11-epoxy-17-hydroxy-3-oxo-γ-lactone-pregn-4-ene-7,21-dicarboxylic acid-7-methyl ester;Eplerenone for system suitability;Eplerenone for peak identification;EPLERENONE
46 prices
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Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 1mg
- 5MG
- 10mg
- 25mg
- 50mg
- 0.1g
- y0001706
- 100MG
- y0001704
- 50
- 200mg
- 10
- 250mg
- 5g
- 25g
- 10mM(in 1mL DMSO)
- y0001705
- 1g
- ManufacturerAK Scientific
- Product numberJ11424
- Product descriptionEplerenone
- Packaging10mg
- Price$74
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ11424
- Product descriptionEplerenone
- Packaging25mg
- Price$159
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberH899
- Product descriptionEplerenone
- Packaging5g
- Price$254
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberH899
- Product descriptionEplerenone
- Packaging25g
- Price$1234
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberRDL0006805
- Product descriptionEPLERENONE-13C-D3 95.00%
- Packaging5MG
- Price$496.51
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0002570
- Product descriptionEPLERENONE 95.00%
- Packaging5MG
- Price$550
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0002570
- Product descriptionEPLERENONE 95.00%
- Packaging10MG
- Price$721.88
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0002570
- Product descriptionEPLERENONE 95.00%
- Packaging100MG
- Price$1732.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8424
- Product descriptionEplerenone
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8424
- Product descriptionEplerenone
- Packaging10mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8424
- Product descriptionEplerenone
- Packaging25mg
- Price$119
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134319
- Product descriptionEplerenone >99%
- Packaging100mg
- Price$510
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134319
- Product descriptionEplerenone >99%
- Packaging250mg
- Price$765
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134319
- Product descriptionEplerenone >99%
- Packaging1g
- Price$1504.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBE164415
- Product descriptionEplerenone
- Packaging10mg
- Price$72
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBE164415
- Product descriptionEplerenone
- Packaging50mg
- Price$212
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | J11424 | Eplerenone | 10mg | $74 | 2021-12-16 | Buy |
AK Scientific | J11424 | Eplerenone | 25mg | $159 | 2021-12-16 | Buy |
AK Scientific | H899 | Eplerenone | 5g | $254 | 2021-12-16 | Buy |
AK Scientific | H899 | Eplerenone | 25g | $1234 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | RDL0006805 | EPLERENONE-13C-D3 95.00% | 5MG | $496.51 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0002570 | EPLERENONE 95.00% | 5MG | $550 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0002570 | EPLERENONE 95.00% | 10MG | $721.88 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0002570 | EPLERENONE 95.00% | 100MG | $1732.5 | 2021-12-16 | Buy |
ApexBio Technology | A8424 | Eplerenone | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
ApexBio Technology | A8424 | Eplerenone | 10mg | $70 | 2021-12-16 | Buy |
ApexBio Technology | A8424 | Eplerenone | 25mg | $119 | 2021-12-16 | Buy |
Biorbyt Ltd | orb134319 | Eplerenone >99% | 100mg | $510 | 2021-12-16 | Buy |
Biorbyt Ltd | orb134319 | Eplerenone >99% | 250mg | $765 | 2021-12-16 | Buy |
Biorbyt Ltd | orb134319 | Eplerenone >99% | 1g | $1504.5 | 2021-12-16 | Buy |
Biosynth Carbosynth | BE164415 | Eplerenone | 10mg | $72 | 2021-12-16 | Buy |
Biosynth Carbosynth | BE164415 | Eplerenone | 50mg | $212 | 2021-12-16 | Buy |
Properties
Melting point :241-243°C
alpha :D +5° (c = 0.437 in chloroform)
Boiling point :597.9±50.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :Store at RT
solubility :DMSO: soluble2mg/mL, clear (warmed)
form :powder
color :white to beige
λmax :240nm(lit.)
Merck :14,3625
InChIKey :UZZAHAKTLYRDOK-MGIDJNSKSA-N
SMILES :[C@@]123[C@@]4(C)CCC(=O)C=C4C[C@@H](C(OC)=O)[C@@]1([H])[C@]1([H])CC[C@]4(CCC(=O)O4)[C@]1(C[C@@]2([H])O3)C |&1:0,1,10,15,17,21,27,29,r|
alpha :D +5° (c = 0.437 in chloroform)
Boiling point :597.9±50.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :Store at RT
solubility :DMSO: soluble2mg/mL, clear (warmed)
form :powder
color :white to beige
λmax :240nm(lit.)
Merck :14,3625
InChIKey :UZZAHAKTLYRDOK-MGIDJNSKSA-N
SMILES :[C@@]123[C@@]4(C)CCC(=O)C=C4C[C@@H](C(OC)=O)[C@@]1([H])[C@]1([H])CC[C@]4(CCC(=O)O4)[C@]1(C[C@@]2([H])O3)C |&1:0,1,10,15,17,21,27,29,r|
Safety Information
Symbol(GHS): | |||||||||||||||||||||||||||||
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Signal word: | Warning | ||||||||||||||||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
Eplerenone is a potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor (IC50 = 122 nM), demonstrating little activity towards other steroid receptors (IC50 > 9 μM for glucocorticoid, androgen, progesterone, and estrogen receptors). Aldosterone antagonists such as this compound have been indicated for the treatment of hypertension and heart failure.Related product price
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Suppliers and manufacturers
Beijing Cooperate Pharmaceutical Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.