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ChemicalBook >> CAS DataBase List >> DOLASTATIN 15

DOLASTATIN 15

DOLASTATIN 15 price.
  • $148 - $1900
  • Product name: DOLASTATIN 15
  • CAS: 123884-00-4
  • MF: C45H68N6O9
  • MW: 837.06
  • EINECS:
  • MDL Number:MFCD00236968
  • Synonyms:DOLASTATIN 15;(5S)-1-[N,N-Dimethyl-L-Val-L-Val-N-methyl-L-Val-L-Pro-L-Pro-L-Hyiv-]-5-benzyl-4-methoxy-1H-pyrrol-2(5H)-one;L-Proline, 1-(1-(N-(N-(N,N-dimethyl-L-valyl)-L-valyl)-N-methyl-L-valyl)-L-prolyl)-, 1-((2,5-dihydro-3-methoxy-5-oxo-2-(phenylmethyl)-1H-pyrrol-1-yl)carbonyl)-2-methylpropyl ester, (S-(R*,R*))-;L-Proline, 1-(1-(N-(N-(N,N-dimethyl-L-valyl)-L-valyl)-N-methyl-L-valyl)-L-propyl)-, 1-((2,5-dihydro-3-methoxy-5-oxo-2-(phenylmethyl)-1H-pyrrol-1-yl)carbonyl)-2-methylpropyl ester, (S-(R*,R*))-;Nsc 617668;(5S)-1-[(2S)-O-(N,N-DIMETHYL-VAL-VAL-N-ME-VAL-PRO-PRO)-2-HYDROXYISOVALERYL]-2-OXO-4-METHOXY-5-BENZYL-3-PYRROLINE;(5S)-1-[(2S)-O-(N,N-VAL-VAL-N-ME-VAL-PRO-PRO)-2-HYDROXYISOVALERYL]-2-OXO-4-METHOXY-5-BENZYL-3-PYRROLINE;Dolastatin 15 (5S)-1-[(2S)-O-(N,N-Dimethyl-Val-Val-N-Me-Val-Pro-Pro)-2-hydroxyisovaleryl]-2-oxo-4-methoxy-5-benzyl-3-pyrroline
8 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • Cayman Chemical
  • TRC
Package
  • 1mg
  • 2mg
  • 5mg
  • 25mg
  • ManufacturerAK Scientific
  • Product number4213CR
  • Product descriptionDolastatin 15
  • Packaging1mg
  • Price$382
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008286
  • Product descriptionDOLASTATIN 15 95.00%
  • Packaging1MG
  • Price$365.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD110329
  • Product descriptionDolastatin 15 (5S)-1-[(2S)-O-(N,N-Dimethyl-Val-Val-N-Me-Val-Pro-Pro)-2-hydroxyisovaleryl]-2-oxo-4-methoxy-5-benzyl-3-pyrroline
  • Packaging1mg
  • Price$148
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD110329
  • Product descriptionDolastatin 15 (5S)-1-[(2S)-O-(N,N-Dimethyl-Val-Val-N-Me-Val-Pro-Pro)-2-hydroxyisovaleryl]-2-oxo-4-methoxy-5-benzyl-3-pyrroline
  • Packaging2mg
  • Price$257
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD110329
  • Product descriptionDolastatin 15 (5S)-1-[(2S)-O-(N,N-Dimethyl-Val-Val-N-Me-Val-Pro-Pro)-2-hydroxyisovaleryl]-2-oxo-4-methoxy-5-benzyl-3-pyrroline
  • Packaging5mg
  • Price$514
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD110329
  • Product descriptionDolastatin 15 (5S)-1-[(2S)-O-(N,N-Dimethyl-Val-Val-N-Me-Val-Pro-Pro)-2-hydroxyisovaleryl]-2-oxo-4-methoxy-5-benzyl-3-pyrroline
  • Packaging25mg
  • Price$1900
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number30144
  • Product descriptionDolastatin 15
  • Packaging1mg
  • Price$255
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberD528508
  • Product descriptionDolastatin 15
  • Packaging1mg
  • Price$170
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4213CR Dolastatin 15 1mg $382 2021-12-16 Buy
American Custom Chemicals Corporation API0008286 DOLASTATIN 15 95.00% 1MG $365.4 2021-12-16 Buy
Biosynth Carbosynth FD110329 Dolastatin 15 (5S)-1-[(2S)-O-(N,N-Dimethyl-Val-Val-N-Me-Val-Pro-Pro)-2-hydroxyisovaleryl]-2-oxo-4-methoxy-5-benzyl-3-pyrroline 1mg $148 2021-12-16 Buy
Biosynth Carbosynth FD110329 Dolastatin 15 (5S)-1-[(2S)-O-(N,N-Dimethyl-Val-Val-N-Me-Val-Pro-Pro)-2-hydroxyisovaleryl]-2-oxo-4-methoxy-5-benzyl-3-pyrroline 2mg $257 2021-12-16 Buy
Biosynth Carbosynth FD110329 Dolastatin 15 (5S)-1-[(2S)-O-(N,N-Dimethyl-Val-Val-N-Me-Val-Pro-Pro)-2-hydroxyisovaleryl]-2-oxo-4-methoxy-5-benzyl-3-pyrroline 5mg $514 2021-12-16 Buy
Biosynth Carbosynth FD110329 Dolastatin 15 (5S)-1-[(2S)-O-(N,N-Dimethyl-Val-Val-N-Me-Val-Pro-Pro)-2-hydroxyisovaleryl]-2-oxo-4-methoxy-5-benzyl-3-pyrroline 25mg $1900 2021-12-16 Buy
Cayman Chemical 30144 Dolastatin 15 1mg $255 2024-03-01 Buy
TRC D528508 Dolastatin 15 1mg $170 2021-12-16 Buy

Properties

Boiling point :954.0±65.0 °C(Predicted)
Density :1.20±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :Methanol: soluble
pka :13.88±0.46(Predicted)
form :White solid.

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Dolastatin 15 is a member of the dolastatin family. Dolastatins are marine natural products isolated from the sea hare Dolabella auricularia with a structure related to Dolastin 10. Dolastatin 15 is an anti-neoplastic pseudopeptide that inhibits Tubulin-dependent GTP hydrolysis to Tubulin but has been shown to bind to the RZX/MAY region. The compound acts as a weak Tubulin inhibitor by binding to the vinca domain of tubulin and induces apoptosis through Bcl-2 phosphorylation in several malignant cell types. Potent inhibitor of the proliferation of murine and cancer cell lines as well as that of hematopoietic progenitor cells. When added to leukemia cultures Dolastin 15 inhibited both immunoglobulin production and cell proliferation.

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