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ChemicalBook >> CAS DataBase List >> DL-THIORPHAN

DL-THIORPHAN

DL-THIORPHAN price.
  • $62 - $1780
  • Product name: DL-THIORPHAN
  • CAS: 76721-89-6
  • MF: C12H15NO3S
  • MW: 253.32
  • EINECS:
  • MDL Number:MFCD00058435
  • Synonyms:N-[(RS)-2-BENZYL-3-MERCAPTOPROPANOYL]-GLYCINE;(+/-)-N-(3-MERCAPTO-2-BENZYLPROPIONYL)GLYCINE;N-ALPHA-(DL-3-MERCAPTO-2-BENZYLPROPANOYL)-GLYCINE;THIORPHAN;THIORPHAN (DL);((RS)-2-BENZYL-3-MERCAPTOPROPIONYL)-GLYCINE;((RS)-2-BENZYL-3-MERCAPTOPROPIONYL)-GLY-OH;2-Mercaptomethyl-3-phenyl-propionylamino-acetic Acid, D,L-3-Mercapto-2-benzylpropanoylglycine,
29 prices
Selected condition：
Brand
  • aablocks
  • AK Scientific
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Chem-Impex
  • Chemtos
  • Crysdot
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • Manufactureraablocks
  • Product numberAA0035MB
  • Product descriptionThiorphan ≥95%
  • Packaging5mg
  • Price$112
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA0035MB
  • Product descriptionThiorphan ≥95%
  • Packaging10mg
  • Price$167
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA0035MB
  • Product descriptionThiorphan ≥95%
  • Packaging25mg
  • Price$310
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA0035MB
  • Product descriptionThiorphan ≥95%
  • Packaging50mg
  • Price$540
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA0035MB
  • Product descriptionThiorphan ≥95%
  • Packaging100mg
  • Price$841
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number9128AJ
  • Product descriptionThiorphan
  • Packaging25mg
  • Price$380
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ62557
  • Product descriptionDL-Thiorphan
  • Packaging25mg
  • Price$459.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberRDL0007169
  • Product descriptionTHIORPHAN-D5 95.00%
  • Packaging5MG
  • Price$496.87
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4349
  • Product descriptionThiorphan
  • Packaging5mg
  • Price$68
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4349
  • Product descriptionThiorphan
  • Packaging10mg
  • Price$129
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4349
  • Product descriptionThiorphan
  • Packaging25mg
  • Price$289
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4349
  • Product descriptionThiorphan
  • Packaging50mg
  • Price$543
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15600
  • Product descriptionThiorphan ≥95%
  • Packaging5mg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15600
  • Product descriptionThiorphan ≥95%
  • Packaging10mg
  • Price$115
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15600
  • Product descriptionThiorphan ≥95%
  • Packaging25mg
  • Price$254
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28692
  • Product descriptionThiorphan-d5
  • Packaging1mg
  • Price$345
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0035MB Thiorphan ≥95% 5mg $112 2021-12-16 Buy
aablocks AA0035MB Thiorphan ≥95% 10mg $167 2021-12-16 Buy
aablocks AA0035MB Thiorphan ≥95% 25mg $310 2021-12-16 Buy
aablocks AA0035MB Thiorphan ≥95% 50mg $540 2021-12-16 Buy
aablocks AA0035MB Thiorphan ≥95% 100mg $841 2021-12-16 Buy
AK Scientific 9128AJ Thiorphan 25mg $380 2021-12-16 Buy
Alfa Aesar J62557 DL-Thiorphan 25mg $459.65 2024-03-01 Buy
American Custom Chemicals Corporation RDL0007169 THIORPHAN-D5 95.00% 5MG $496.87 2021-12-16 Buy
ApexBio Technology C4349 Thiorphan 5mg $68 2021-12-16 Buy
ApexBio Technology C4349 Thiorphan 10mg $129 2021-12-16 Buy
ApexBio Technology C4349 Thiorphan 25mg $289 2021-12-16 Buy
ApexBio Technology C4349 Thiorphan 50mg $543 2021-12-16 Buy
Cayman Chemical 15600 Thiorphan ≥95% 5mg $62 2024-03-01 Buy
Cayman Chemical 15600 Thiorphan ≥95% 10mg $115 2024-03-01 Buy
Cayman Chemical 15600 Thiorphan ≥95% 25mg $254 2024-03-01 Buy
Cayman Chemical 28692 Thiorphan-d5 1mg $345 2021-12-16 Buy

Properties

Melting point :138-140 °C
Boiling point :524.0±50.0 °C(Predicted)
Density :1.246±0.06 g/cm3(Predicted)
RTECS :MC0596440
storage temp. :-15°C
solubility :ethanol: 50 mg/mL, clear, colorless
form :White solid
pka :3.48±0.10(Predicted)
color :White to Off-White
BRN :4872101
CAS DataBase Reference :76721-89-6

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Thiorphan is a potent inhibitor of neprilysin, a membrane metallo-endopeptidase that cleaves peptide hormones, such as enkephalins, glucagon, and bradykinin (Ki = 4-140 nM). It is much less effective against neprilysin-2 (IC50 = 22.1 μM), angiotensin-converting enzyme, and endothelin-converting enzyme-1. Thiorphan can be produced in vivo via the metabolism of the prodrug acetorphan. Neprilysin is overexpressed in many forms of cancer and may play a role in protecting against Alzheimer’s disease.

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