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ChemicalBook >> CAS DataBase List >> Cucurbitacin E

Cucurbitacin E

Cucurbitacin E price.
  • $35 - $1540
  • Product name: Cucurbitacin E
  • CAS: 18444-66-1
  • MF: C32H44O8
  • MW: 556.69
  • EINECS:242-325-2
  • MDL Number:MFCD00135936
  • Synonyms:A-ELATERIN;ALPHA-ELATERIN;CUCURBITACIN E;CUCURBITACIN E(SH);19-nor-9-beta,10-alpha-lanosta-1,5,23-triene-3,11,22-trione,2,16-alpha,20,25-t ;25-acetate ;alpha-elaterine ;cucurbitacine-e
36 prices
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Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 20mg
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0474-M025
  • Product descriptionCucurbitacin E ≥98%(HPLC)
  • Packaging25mg
  • Price$560
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0474-M001
  • Product descriptionCucurbitacin E ≥98%(HPLC)
  • Packaging1mg
  • Price$35
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0059
  • Product descriptionCucurbitacin E
  • Packaging1mg
  • Price$144
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0059
  • Product descriptionCucurbitacin E
  • Packaging10mg
  • Price$434
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA513376
  • Product descriptionCucurbitacin E 98+%
  • Packaging5mg
  • Price$118
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA513376
  • Product descriptionCucurbitacin E 98+%
  • Packaging10mg
  • Price$195
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA513376
  • Product descriptionCucurbitacin E 98+%
  • Packaging25mg
  • Price$310
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA513376
  • Product descriptionCucurbitacin E 98+%
  • Packaging50mg
  • Price$481
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA513376
  • Product descriptionCucurbitacin E 98+%
  • Packaging100mg
  • Price$700
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberSHG0007173
  • Product descriptionCUCURBITACIN E 95.00%
  • Packaging10MG
  • Price$967.77
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN2791
  • Product descriptionCucurbitacin E
  • Packaging20mg
  • Price$365
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN90154
  • Product descriptionCucurbitacin E ≥98%
  • Packaging10mg
  • Price$368
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberSY073793
  • Product descriptionCucurbitacinE,98%,fromCucumismeloL.
  • Packaging10mg
  • Price$490.91
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2360
  • Product descriptionCucurbitacin E
  • Packaging5mg
  • Price$89
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2360
  • Product descriptionCucurbitacin E
  • Packaging10mg
  • Price$159
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2360
  • Product descriptionCucurbitacin E
  • Packaging25mg
  • Price$309
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CN2-0474-M025 Cucurbitacin E ≥98%(HPLC) 25mg $560 2021-12-16 Buy
Adipogen Life Sciences AG-CN2-0474-M001 Cucurbitacin E ≥98%(HPLC) 1mg $35 2021-12-16 Buy
AK Scientific Y0059 Cucurbitacin E 1mg $144 2021-12-16 Buy
AK Scientific Y0059 Cucurbitacin E 10mg $434 2021-12-16 Buy
Ambeed A513376 Cucurbitacin E 98+% 5mg $118 2021-12-16 Buy
Ambeed A513376 Cucurbitacin E 98+% 10mg $195 2021-12-16 Buy
Ambeed A513376 Cucurbitacin E 98+% 25mg $310 2021-12-16 Buy
Ambeed A513376 Cucurbitacin E 98+% 50mg $481 2021-12-16 Buy
Ambeed A513376 Cucurbitacin E 98+% 100mg $700 2021-12-16 Buy
American Custom Chemicals Corporation SHG0007173 CUCURBITACIN E 95.00% 10MG $967.77 2021-12-16 Buy
ApexBio Technology N2791 Cucurbitacin E 20mg $365 2021-12-16 Buy
Arctom CFN90154 Cucurbitacin E ≥98% 10mg $368 2021-12-16 Buy
Arctom SY073793 CucurbitacinE,98%,fromCucumismeloL. 10mg $490.91 2021-12-16 Buy
AvaChem 2360 Cucurbitacin E 5mg $89 2021-12-16 Buy
AvaChem 2360 Cucurbitacin E 10mg $159 2021-12-16 Buy
AvaChem 2360 Cucurbitacin E 25mg $309 2021-12-16 Buy

Properties

Melting point :228-234°C
alpha :D -59° (c = 0.7 in chloroform)
Boiling point :545.56°C (rough estimate)
Density :1.1059 (rough estimate)
refractive index :1.4900 (estimate)
storage temp. :-20°C
solubility :DMSO: soluble15mg/mL, clear
form :powder
pka :8.51±0.70(Predicted)
color :white to beige
optical activity :[α]/D -60 to -75°, c = 0.7 (CDCl3)
InChIKey :NDYMQXYDSVBNLL-MUYMLXPFSA-N
LogP :3.150 (est)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

Cucurbitacin E is a plant-derived triterpene that has diverse biological activities. At a concentration of 10 pM, it reduces MPP+-induced death of neuronal PC12 cells through inhibition of autophagy in vitro. Cucurbitacin E inhibits growth of T24 bladder, MDA-MB-468 and MCF-7 breast, PC3 prostate, and colorectal cancer cell lines (IC50s = 50-1,000 nM) through induction of G2/M arrest and apoptosis. It increases bilirubin binding to human serum albumin (HSA) in human plasma in a dose-dependent manner. Cucurbitacin E also inhibits depolymerization of actin filaments isolated from rabbit skeletal muscle actin and in HeLa cells.

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