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ChemicalBook >> CAS DataBase List >> CALPHOSTIN C

CALPHOSTIN C

CALPHOSTIN C price.
  • $142 - $890
  • Product name: CALPHOSTIN C
  • CAS: 121263-19-2
  • MF: C44H38O14
  • MW: 790.76
  • EINECS:
  • MDL Number:MFCD00133155
  • Synonyms:CALPHOSTIN C;CALPHOSTIN C FROM CLADOSPORIUMCLADOSPORI OIDES;UCN-1028C;(R)-Calphostin C;1-[(R)-2-(4-Hydroxyphenoxycarbonyloxy)propyl]-2,6,7,11-tetramethoxy-4,9-dihydroxy-12-[(R)-2-(benzoyloxy)propyl]-3,10-dihydroperylene-3,10-dione;4,9-Dihydroxy-12-[(R)-2-(4-hydroxyphenyloxy)carbonyloxypropyl]-2,6,7,11-tetramethoxy-1-[(R)-2-benzoyloxypropyl]perylene-3,10-dione;Calphostin C,98%;Calphostin CUCN-1028C
13 prices
Selected condition：
Brand
  • Adipogen Life Sciences
  • Alfa Aesar
  • ApexBio Technology
  • Cayman Chemical
  • CSNpharm
  • Sigma-Aldrich
  • Tocris
  • Usbiological
Package
  • 50μg
  • 100ug
  • 100μg
  • 0.1mg
  • 500μg
  • 1mg
  • 100U
  • 100microg
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0430-M001
  • Product descriptionCalphostinC ≥95%(HPLC)
  • Packaging1mg
  • Price$890
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60647
  • Product descriptionCalphostin C, 95%
  • Packaging100microg
  • Price$238
  • Updated2023-06-20
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6807
  • Product descriptionCalphostinC
  • Packaging100ug
  • Price$308
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15383
  • Product descriptionCalphostin C ≥95%
  • Packaging100μg
  • Price$142
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15383
  • Product descriptionCalphostin C ≥95%
  • Packaging500μg
  • Price$603
  • Updated2024-03-01
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN22738
  • Product descriptionCalphostinC
  • Packaging1mg
  • Price$436
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number208725
  • Product descriptionCalphostin C, Cladosporium cladosporioides - CAS 121263-19-2 - Calbiochem Acellpermeable,highlyspecificinhibitorofproteinkinaseC(IC??=50nM)t
  • Packaging50μg
  • Price$154
  • Updated2023-01-07
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberC6303
  • Product descriptionCalphostin C from Cladosporium cladosporioides ≥90% (HPLC), powder
  • Packaging0.1mg
  • Price$254.4
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number208725
  • Product descriptionCalphostin C, Cladosporium cladosporioides - CAS 121263-19-2 - Calbiochem Acellpermeable,highlyspecificinhibitorofproteinkinaseC(IC??=50nM)t
  • Packaging100μg
  • Price$264
  • Updated2023-01-07
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberC6303
  • Product descriptionCalphostin C from Cladosporium cladosporioides ≥90% (HPLC), powder
  • Packaging1mg
  • Price$812
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number1626
  • Product descriptionCalphostinC ≥98%(HPLC)
  • Packaging100U
  • Price$212
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number207099
  • Product descriptionCalphostin C
  • Packaging100ug
  • Price$342
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product numberC1035-38
  • Product descriptionCalphostin C
  • Packaging100ug
  • Price$426
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CN2-0430-M001 CalphostinC ≥95%(HPLC) 1mg $890 2021-12-16 Buy
Alfa Aesar J60647 Calphostin C, 95% 100microg $238 2023-06-20 Buy
ApexBio Technology B6807 CalphostinC 100ug $308 2021-12-16 Buy
Cayman Chemical 15383 Calphostin C ≥95% 100μg $142 2024-03-01 Buy
Cayman Chemical 15383 Calphostin C ≥95% 500μg $603 2024-03-01 Buy
CSNpharm CSN22738 CalphostinC 1mg $436 2021-12-16 Buy
Sigma-Aldrich 208725 Calphostin C, Cladosporium cladosporioides - CAS 121263-19-2 - Calbiochem Acellpermeable,highlyspecificinhibitorofproteinkinaseC(IC??=50nM)t 50μg $154 2023-01-07 Buy
Sigma-Aldrich C6303 Calphostin C from Cladosporium cladosporioides ≥90% (HPLC), powder 0.1mg $254.4 2024-03-01 Buy
Sigma-Aldrich 208725 Calphostin C, Cladosporium cladosporioides - CAS 121263-19-2 - Calbiochem Acellpermeable,highlyspecificinhibitorofproteinkinaseC(IC??=50nM)t 100μg $264 2023-01-07 Buy
Sigma-Aldrich C6303 Calphostin C from Cladosporium cladosporioides ≥90% (HPLC), powder 1mg $812 2024-03-01 Buy
Tocris 1626 CalphostinC ≥98%(HPLC) 100U $212 2021-12-16 Buy
Usbiological 207099 Calphostin C 100ug $342 2021-12-16 Buy
Usbiological C1035-38 Calphostin C 100ug $426 2021-12-16 Buy

Properties

Boiling point :1039.8±65.0 °C(Predicted)
Density :1.48±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMF: 1 mg/mL
form :powder
pka :7.30±0.20(Predicted)
color :red to brown

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Calphostin C is a metabolite of the fungus C. cladosporioides that specifically inhibits protein kinase C (PKC) (IC50 = 50 nM versus an IC50 > 50 μM for PKA) by competing at the binding site for diacylglycerol and phorbol esters. As a polycyclic hydrocarbon with strong absorbance in the visible and ultraviolet ranges, activation of this compound is strictly dependent on exposure to light. Independent of PKC, calphostin C also directly inhibits phospholipase D1 and D2 (IC50s = 100 nM). It demonstrates antitumor activity, inhibiting cell growth and promoting apoptosis in HeLa S3 and MCF-7 cells with IC50 values of 0.23 and 0.18 μM, respectively.

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