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ChemicalBook >> CAS DataBase List >> CA-074 ME

CA-074 ME

CA-074 ME price.
  • $55 - $2228
  • Product name: CA-074 ME
  • CAS: 147859-80-1
  • MF: C19H31N3O6
  • MW: 397.47
  • EINECS:
  • MDL Number:MFCD00797532
  • Synonyms:N-(L-3-TRANS-PROPYLCARBONYL-OXIRANE-2-CARBONYL)-L-ISOLEUCYL-L-PROLINE METHYL ESTER;L-trans-Epoxysuccinyl(propylamide)-Ile-P;(L-3-Trans-(propylcarbamoyl)oxirane-2-carbony;L-trans-Epoxysuccinic Ile-Pro-OMe Propylamide;L-trans-Epoxysuccinyl-isoleucyl-proline methyl ester propylamide;CA-074 methyl ester;(L-3-trans-(Propylcarbamyl)oxirane-2-carbonyl)-L-isoleucyl-L-proline methyl ester;CA-074(OME)
31 prices
Selected condition：
Brand
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Chemenu
  • Chem-Impex
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • TRC
Package
  • 10mM(in 1mL DMSO)
  • 500μg
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAlfa Aesar
  • Product numberJ64737
  • Product descriptionCathepsin B Inhibitor IV
  • Packaging10mg
  • Price$602
  • Updated2023-06-20
  • Buy
  • ManufacturerAmbeed
  • Product numberA917874
  • Product descriptionCA-074 methyl ester 95+%
  • Packaging1mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA917874
  • Product descriptionCA-074 methyl ester 95+%
  • Packaging5mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA917874
  • Product descriptionCA-074 methyl ester 95+%
  • Packaging10mg
  • Price$193
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA917874
  • Product descriptionCA-074 methyl ester 95+%
  • Packaging25mg
  • Price$322
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA917874
  • Product descriptionCA-074 methyl ester 95+%
  • Packaging100mg
  • Price$596
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA917874
  • Product descriptionCA-074 methyl ester 95+%
  • Packaging250mg
  • Price$860
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA917874
  • Product descriptionCA-074 methyl ester 95+%
  • Packaging1g
  • Price$2228
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000094
  • Product descriptionCA-074 ME 95.00%
  • Packaging5MG
  • Price$898.88
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8239
  • Product descriptionCA-074Me
  • Packaging1mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8239
  • Product descriptionCA-074Me
  • Packaging10mM(in 1mL DMSO)
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8239
  • Product descriptionCA-074Me
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8239
  • Product descriptionCA-074Me
  • Packaging10mg
  • Price$210
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8239
  • Product descriptionCA-074Me
  • Packaging25mg
  • Price$390
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18469
  • Product descriptionCA-074 methyl ester ≥98%
  • Packaging500μg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18469
  • Product descriptionCA-074 methyl ester ≥98%
  • Packaging1mg
  • Price$109
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Alfa Aesar J64737 Cathepsin B Inhibitor IV 10mg $602 2023-06-20 Buy
Ambeed A917874 CA-074 methyl ester 95+% 1mg $55 2021-12-16 Buy
Ambeed A917874 CA-074 methyl ester 95+% 5mg $110 2021-12-16 Buy
Ambeed A917874 CA-074 methyl ester 95+% 10mg $193 2021-12-16 Buy
Ambeed A917874 CA-074 methyl ester 95+% 25mg $322 2021-12-16 Buy
Ambeed A917874 CA-074 methyl ester 95+% 100mg $596 2021-12-16 Buy
Ambeed A917874 CA-074 methyl ester 95+% 250mg $860 2021-12-16 Buy
Ambeed A917874 CA-074 methyl ester 95+% 1g $2228 2021-12-16 Buy
American Custom Chemicals Corporation INB0000094 CA-074 ME 95.00% 5MG $898.88 2021-12-16 Buy
ApexBio Technology A8239 CA-074Me 1mg $70 2021-12-16 Buy
ApexBio Technology A8239 CA-074Me 10mM(in 1mL DMSO) $105 2021-12-16 Buy
ApexBio Technology A8239 CA-074Me 5mg $120 2021-12-16 Buy
ApexBio Technology A8239 CA-074Me 10mg $210 2021-12-16 Buy
ApexBio Technology A8239 CA-074Me 25mg $390 2021-12-16 Buy
Cayman Chemical 18469 CA-074 methyl ester ≥98% 500μg $62 2024-03-01 Buy
Cayman Chemical 18469 CA-074 methyl ester ≥98% 1mg $109 2024-03-01 Buy

Properties

Melting point :153-155°C
Boiling point :666.3±55.0 °C(Predicted)
Density :1.212±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO
pka :13.38±0.40(Predicted)
form :Solid
color :White to Off-White
InChIKey :XGWSRLSPWIEMLQ-YTFOTSKYSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

CA-074 methyl ester is a cell-permeable inhibitor of cathepsin B and L in vivo and in whole cells. The methyl ester is hydrolyzed by intracellular esterases releasing the active inhibitor, CA-074. This compound has primarily been used to study the role of cathepsin B in neurodegeneration, cancer cell metastasis, necrosis, and rheumatoid arthritis.

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