BAY 11-7082
- $24 - $2304
- Product name: BAY 11-7082
- CAS: 19542-67-7
- MF: C10H9NO2S
- MW: 207.25
- EINECS:
- MDL Number:MFCD00712162
- Synonyms:BAY 11-7082;BAY 11-7821;(E)-3-(4-METHYLPHENYLSULFONYL)-2-PROPENENITRILE;(E)-3-tosylacrylonitrile;(E)-3-(p-Toluenesulfonyl)acrylonitrile;BAY11-7082/BAY117082;BAY11-7082,BAY 117821;(2E)-3-[(4-METHYLPHENYL)SULFONYL]-2-PROPENENITRILE
41 prices
Selected condition:
Brand
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- Axon Medchem
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 2x10mg
- 25mg
- 50mg
- 10
- 5mg
- 10mg
- 20mg
- 100mg
- 250mg
- 1G
- 5g
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-0013-M050
- Product descriptionBAY 11-7082 ≥99%(NMR)
- Packaging50mg
- Price$280
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2252AH
- Product description3-(Toluene-4-sulfonyl)-acrylonitrile
- Packaging50mg
- Price$131
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA107077
- Product descriptionBAY 11-7082 98+%
- Packaging5mg
- Price$24
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA107077
- Product descriptionBAY 11-7082 98+%
- Packaging10mg
- Price$31
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA107077
- Product descriptionBAY 11-7082 98+%
- Packaging250mg
- Price$169
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4210
- Product descriptionBay11-7821(BAY11-7082)
- Packaging10mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4210
- Product descriptionBay11-7821(BAY11-7082)
- Packaging25mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4210
- Product descriptionBay11-7821(BAY11-7082)
- Packaging50mg
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4210
- Product descriptionBay11-7821(BAY11-7082)
- Packaging100mg
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60021
- Product descriptionBAY 11-7082
- Packaging20mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2132
- Product descriptionBAY11-7082-BAY11-7821 99%
- Packaging2x10mg
- Price$143
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10010266
- Product descriptionBAY 11-7082 ≥98%
- Packaging5mg
- Price$49
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10010266
- Product descriptionBAY 11-7082 ≥98%
- Packaging10mg
- Price$92
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10010266
- Product descriptionBAY 11-7082 ≥98%
- Packaging25mg
- Price$216
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10010266
- Product descriptionBAY 11-7082 ≥98%
- Packaging50mg
- Price$380
- Updated2024-03-01
- Buy
- ManufacturerChem-Impex
- Product number42196
- Product descriptionBAY11-7082,≥98%(HPLC) ≥98%(HPLC)
- Packaging100MG
- Price$37.27
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Adipogen Life Sciences | AG-CR1-0013-M050 | BAY 11-7082 ≥99%(NMR) | 50mg | $280 | 2021-12-16 | Buy |
AK Scientific | 2252AH | 3-(Toluene-4-sulfonyl)-acrylonitrile | 50mg | $131 | 2021-12-16 | Buy |
Ambeed | A107077 | BAY 11-7082 98+% | 5mg | $24 | 2021-12-16 | Buy |
Ambeed | A107077 | BAY 11-7082 98+% | 10mg | $31 | 2021-12-16 | Buy |
Ambeed | A107077 | BAY 11-7082 98+% | 250mg | $169 | 2021-12-16 | Buy |
ApexBio Technology | A4210 | Bay11-7821(BAY11-7082) | 10mg | $60 | 2021-12-16 | Buy |
ApexBio Technology | A4210 | Bay11-7821(BAY11-7082) | 25mg | $120 | 2021-12-16 | Buy |
ApexBio Technology | A4210 | Bay11-7821(BAY11-7082) | 50mg | $190 | 2021-12-16 | Buy |
ApexBio Technology | A4210 | Bay11-7821(BAY11-7082) | 100mg | $300 | 2021-12-16 | Buy |
Arctom | CFN60021 | BAY 11-7082 | 20mg | $218 | 2021-12-16 | Buy |
Axon Medchem | Axon2132 | BAY11-7082-BAY11-7821 99% | 2x10mg | $143 | 2021-12-16 | Buy |
Cayman Chemical | 10010266 | BAY 11-7082 ≥98% | 5mg | $49 | 2024-03-01 | Buy |
Cayman Chemical | 10010266 | BAY 11-7082 ≥98% | 10mg | $92 | 2024-03-01 | Buy |
Cayman Chemical | 10010266 | BAY 11-7082 ≥98% | 25mg | $216 | 2024-03-01 | Buy |
Cayman Chemical | 10010266 | BAY 11-7082 ≥98% | 50mg | $380 | 2024-03-01 | Buy |
Chem-Impex | 42196 | BAY11-7082,≥98%(HPLC) ≥98%(HPLC) | 100MG | $37.27 | 2021-12-16 | Buy |
Properties
Melting point :133-135℃
Boiling point :397.6±42.0 °C(Predicted)
Density :1.237±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :DMSO: 25 mg/mL, soluble
form :solid
color :white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Boiling point :397.6±42.0 °C(Predicted)
Density :1.237±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :DMSO: 25 mg/mL, soluble
form :solid
color :white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Safety Information
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Signal word: | Warning | ||||||||||||||||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
BAY 11-7082, a potential anti-inflammatory agent, is an irreversible inhibitor of IKK α and phosphorylation of cytokine-inducible IκBα (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-α, NFKBIA; IC50=10 μM). In intact HUVECs, it inhibits TNFα-induced phosphorylation and degradation of IκBa (NFKBIA) without affecting constitutive phosphorylation. Inhibition of ιBα phosphorylation and degradation results in the inactivation of NFκB and thereby inhibits the expression of endothelial-leukocyte adhesion molecules: E-selectin, VCAM-1 and ICAM-11. BAY 11-7082 has also demonstrated stimulation of the stress-activated protein kinases, p38 and JNK-1.Related product price
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