Aminoquinol
- $30 - $560
- Product name: Aminoquinol
- CAS: 10023-54-8
- MF: C26H31Cl2N3
- MW: 456.45
- EINECS:
- MDL Number:MFCD01709344
- Synonyms:Aminoquinol;7-Chloro-2-(o-chlorostyryl)-4-[[4-(diethylamino)-1-methylbutyl]amino]quinoline;N-*4*-{7-Chloro-2-[2-(2-chloro-phenyl)-vinyl]-quin olin-4-yl}-N*1*,N*1*-diethyl-pentane-1,4-diami;N-*4*-{7-Chloro-2-[2-(2-chloro-phenyl)-vinyl]-quinolin-4-yl}-N*1*,N*1*-diethyl-pentane-1,4-dia;N4-{7-chloro-2-[2-(2-chlorophenyl)vinyl]-4-quinolinyl}-N1,N1-diethyl-1,4-pentanediamine tris(phosphate);1,4-Pentanediamine, N4-[7-chloro-2-[2-(2-chlorophenyl)ethenyl]-4-quinolinyl]-N1,N1-diethyl-;Aminoquinol DISCONTINUED. Please see C609759.
4 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Aronis compounds
- Matrix Scientific
Package
- 5MG
- 20mg
- 1g
- ManufacturerAK Scientific
- Product number7133AC
- Product descriptionN4-{7-Chloro-2-[2-(2-chloro-phenyl)-vinyl]-quinolin-4-yl}-N1,N1-diethyl-pentane-1,4-diamine
- Packaging1g
- Price$560
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0025379
- Product descriptionAMINOQUINOL 95.00%
- Packaging5MG
- Price$501.2
- Updated2021-12-16
- Buy
- ManufacturerAronis compounds
- Product numbere00599
- Product descriptionN4-{7-chloro-2-[2-(2-chlorophenyl)vinyl]-4-quinolinyl}-N1,N1-diethyl-1,4-pentanediaminetris(phosphate)
- Packaging20mg
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerMatrix Scientific
- Product number009881
- Product descriptionN-*4*-{7-Chloro-2-[2-(2-chloro-phenyl)-vinyl]-quinolin-4-yl}-N*1*,N*1*-diethyl-pentane-1,4-diamine triphosphate
- Packaging1g
- Price$378
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 7133AC | N4-{7-Chloro-2-[2-(2-chloro-phenyl)-vinyl]-quinolin-4-yl}-N1,N1-diethyl-pentane-1,4-diamine | 1g | $560 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0025379 | AMINOQUINOL 95.00% | 5MG | $501.2 | 2021-12-16 | Buy |
Aronis compounds | e00599 | N4-{7-chloro-2-[2-(2-chlorophenyl)vinyl]-4-quinolinyl}-N1,N1-diethyl-1,4-pentanediaminetris(phosphate) | 20mg | $30 | 2021-12-16 | Buy |
Matrix Scientific | 009881 | N-*4*-{7-Chloro-2-[2-(2-chloro-phenyl)-vinyl]-quinolin-4-yl}-N*1*,N*1*-diethyl-pentane-1,4-diamine triphosphate | 1g | $378 | 2021-12-16 | Buy |
Properties
Melting point :223-225°
Boiling point :597.1±50.0 °C(Predicted)
Density :1.191±0.06 g/cm3(Predicted)
storage temp. :RT
solubility :Soluble in DMSO (up to 25 mg/ml with warming).
form :solid
pka :10.47±0.25(Predicted)
color :Light brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Boiling point :597.1±50.0 °C(Predicted)
Density :1.191±0.06 g/cm3(Predicted)
storage temp. :RT
solubility :Soluble in DMSO (up to 25 mg/ml with warming).
form :solid
pka :10.47±0.25(Predicted)
color :Light brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Safety Information
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Signal word: | Danger | |||||||||||||||||||||
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Description
XIB4035 (10023-54-8) is a novel small molecule thought to be an agonist at the glial cell line-derived neurotrophic factor (GDNF) family receptor GFRα-1. It inhibits radiolabeled GDNF binding in Neuro-2A cells in a concentration dependent manner IC50?= 10.4 μM. Like GDNF, XIB4035 induced Ret autophosphorylation and promoted neurite outgrowth in Neuro-2A cells.1?Recent studies indicate that it enhances GFRα family receptor signaling in conjunction with ligand stimulation. Effective treatment for small-fiber neuropathy in mouse models of the disease.2,3? GDNF agonists may be a new class of Parkinson’s disease therapeutics.4Related product price
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