AGM-1470
- $61 - $9980
- Product name: AGM-1470
- CAS: 129298-91-5
- MF: C19H28ClNO6
- MW: 401.88
- EINECS:
- MDL Number:MFCD00870281
- Synonyms:NSC642492;O-(chloroacetylcarbamoyl)fumagillol;O-(CHLOROACETYLCARBAMOYL)FUMAGILLOLTNP-470 AGM-1470;[(3R,4S,5S,6R)-5-Methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl] N-(2-chloroacetyl)carbamate;AGM-1470;Carbamic acid, (chloroacetyl)-, (3R,4S,5S,6R)-5-methoxy-4-[ (2R,3R)-2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]oct-6-yl ester;Tnp-470;N-(2-Chloroacetyl)carbamicacid(3R,4S,5S,6R)-5-Methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]oct-6-ylester
20 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- ChemScene
- JR MediChem
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 5mg
- 10mg
- 25mg
- 100mg
- 500mg
- 5g
- 1 mg
- ManufacturerAK Scientific
- Product number7768BA
- Product descriptionO-(Chloroacetylcarbamoyl)fumagillol
- Packaging10mg
- Price$302
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0009209
- Product descriptionTNP-470 95.00%
- Packaging10MG
- Price$726.44
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3622
- Product descriptionTNP-470
- Packaging5mg
- Price$104
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3622
- Product descriptionTNP-470
- Packaging10mg
- Price$198
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3622
- Product descriptionTNP-470
- Packaging25mg
- Price$469
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16449
- Product descriptionTNP-470 ≥98%
- Packaging1 mg
- Price$61
- Updated2023-06-20
- Buy
- ManufacturerCayman Chemical
- Product number16449
- Product descriptionTNP-470 ≥98%
- Packaging5mg
- Price$91
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16449
- Product descriptionTNP-470 ≥98%
- Packaging10mg
- Price$173
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16449
- Product descriptionTNP-470 ≥98%
- Packaging25mg
- Price$410
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-8106
- Product descriptionTNP-470 >99.0%
- Packaging5mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-8106
- Product descriptionTNP-470 >99.0%
- Packaging10mg
- Price$550
- Updated2021-12-16
- Buy
- ManufacturerJR MediChem
- Product numberJR6-L3045
- Product descriptionTNP-470 96%
- Packaging5g
- Price$9980
- Updated2021-12-16
- Buy
- ManufacturerJR MediChem
- Product numberJR6-L3045
- Product descriptionTNP-470 96%
- Packaging500mg
- Price$1698
- Updated2021-12-16
- Buy
- ManufacturerJR MediChem
- Product numberJR6-L3045
- Product descriptionTNP-470 96%
- Packaging25mg
- Price$198
- Updated2021-12-16
- Buy
- ManufacturerJR MediChem
- Product numberJR6-L3045
- Product descriptionTNP-470 96%
- Packaging5mg
- Price$68
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number48973
- Product descriptionTNP-470
- Packaging100mg
- Price$1325
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 7768BA | O-(Chloroacetylcarbamoyl)fumagillol | 10mg | $302 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0009209 | TNP-470 95.00% | 10MG | $726.44 | 2021-12-16 | Buy |
ApexBio Technology | C3622 | TNP-470 | 5mg | $104 | 2021-12-16 | Buy |
ApexBio Technology | C3622 | TNP-470 | 10mg | $198 | 2021-12-16 | Buy |
ApexBio Technology | C3622 | TNP-470 | 25mg | $469 | 2021-12-16 | Buy |
Cayman Chemical | 16449 | TNP-470 ≥98% | 1 mg | $61 | 2023-06-20 | Buy |
Cayman Chemical | 16449 | TNP-470 ≥98% | 5mg | $91 | 2024-03-01 | Buy |
Cayman Chemical | 16449 | TNP-470 ≥98% | 10mg | $173 | 2024-03-01 | Buy |
Cayman Chemical | 16449 | TNP-470 ≥98% | 25mg | $410 | 2024-03-01 | Buy |
ChemScene | CS-8106 | TNP-470 >99.0% | 5mg | $180 | 2021-12-16 | Buy |
ChemScene | CS-8106 | TNP-470 >99.0% | 10mg | $550 | 2021-12-16 | Buy |
JR MediChem | JR6-L3045 | TNP-470 96% | 5g | $9980 | 2021-12-16 | Buy |
JR MediChem | JR6-L3045 | TNP-470 96% | 500mg | $1698 | 2021-12-16 | Buy |
JR MediChem | JR6-L3045 | TNP-470 96% | 25mg | $198 | 2021-12-16 | Buy |
JR MediChem | JR6-L3045 | TNP-470 96% | 5mg | $68 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 48973 | TNP-470 | 100mg | $1325 | 2021-12-16 | Buy |
Properties
Melting point :90-93°C
alpha :D24 -46.6° (c = 0.44 in CHCl3)
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: >15mg/mL
form :White to light yellow solid
pka :7.19±0.46(Predicted)
color :White to Pale Yellow Waxy
Stability :Hygroscopic
alpha :D24 -46.6° (c = 0.44 in CHCl3)
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: >15mg/mL
form :White to light yellow solid
pka :7.19±0.46(Predicted)
color :White to Pale Yellow Waxy
Stability :Hygroscopic
Safety Information
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Signal word: | Warning | ||||||||||||||||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
TNP-470 is a synthetic analog of fumagillin that inhibits angiogenesis. It irreversibly inactivates methionine aminopeptidase-2 (MetAP2; IC50 = 2 μM), blocking endothelial cell proliferation in vitro and angiogenesis in vivo. It is without effect on MetAP1. TNP-470 has therapeutic potential in cancer and microsporidiosis.More related product prices
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Suppliers and manufacturers
CONIER CHEM AND PHARMA LIMITED
HANGZHOU CLAP TECHNOLOGY CO.,LTD
LEAPCHEM CO., LTD.
Aladdin Scientific
3B Pharmachem (Wuhan) International Co.,Ltd.
Guangzhou Isun Pharmaceutical Co., Ltd
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Sigma-Aldrich
Hubei Yangxin Medical Technology Co., Ltd.