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ChemicalBook >> CAS DataBase List >> (S)-2-[(Bis(3,5-bis(trifluoromethyl)phenyl)trimethylsilanyloxy)methyl]pyrrolidine, (S)-2-[(Bis(3,5-bis(trifluoromethyl)phenyl)trimethylsilyloxy)methyl]pyrrolidine, (S)-α,α-[3,5-Bis(trifluoromethyl)phenyl]prolinol trimethylsilyl ether

(S)-2-[(Bis(3,5-bis(trifluoromethyl)phenyl)trimethylsilanyloxy)methyl]pyrrolidine, (S)-2-[(Bis(3,5-bis(trifluoromethyl)phenyl)trimethylsilyloxy)methyl]pyrrolidine, (S)-α,α-[3,5-Bis(trifluoromethyl)phenyl]prolinol trimethylsilyl ether

(S)-2-[(Bis(3,5-bis(trifluoromethyl)phenyl)trimethylsilanyloxy)methyl]pyrrolidine, (S)-2-[(Bis(3,5-bis(trifluoromethyl)phenyl)trimethylsilyloxy)methyl]pyrrolidine, (S)-α,α-[3,5-Bis(trifluoromethyl)phenyl]prolinol trimethylsilyl ether price.
18 prices
Selected condition：
Brand
  • Alichem
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • Chemenu
  • Crysdot
  • JR MediChem
  • Matrix Scientific
  • Sigma-Aldrich
  • TRC
Package
  • 100mg
  • 250mg
  • 500mg
  • 1G
  • 2g
  • 2.5g
  • 5g
  • ManufacturerAlichem
  • Product number848821614
  • Product description(S)-2-(Bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine
  • Packaging5g
  • Price$610
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberORS0001315
  • Product description(S)-ALPHA,ALPHA-BIS[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-2-PYRROLIDINEMETHANOL TRIMETHYLSILYL ETHER 97.00%
  • Packaging1G
  • Price$735.54
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberORS0001315
  • Product description(S)-ALPHA,ALPHA-BIS[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-2-PYRROLIDINEMETHANOL TRIMETHYLSILYL ETHER 97.00%
  • Packaging5G
  • Price$1130.28
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB100522
  • Product description(S)-2-[Bis[3,5-bis(trifluoromethyl)phenyl](trimethylsilyloxy)methyl]pyrrolidine
  • Packaging100mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB100522
  • Product description(S)-2-[Bis[3,5-bis(trifluoromethyl)phenyl](trimethylsilyloxy)methyl]pyrrolidine
  • Packaging250mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB100522
  • Product description(S)-2-[Bis[3,5-bis(trifluoromethyl)phenyl](trimethylsilyloxy)methyl]pyrrolidine
  • Packaging500mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB100522
  • Product description(S)-2-[Bis[3,5-bis(trifluoromethyl)phenyl](trimethylsilyloxy)methyl]pyrrolidine
  • Packaging1g
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB100522
  • Product description(S)-2-[Bis[3,5-bis(trifluoromethyl)phenyl](trimethylsilyloxy)methyl]pyrrolidine
  • Packaging2g
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM132747
  • Product description(S)-2-(bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine 95%
  • Packaging5g
  • Price$524
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD42000193
  • Product description(S)-2-(Bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine 95+%
  • Packaging1g
  • Price$203
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD42000193
  • Product description(S)-2-(Bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine 95+%
  • Packaging5g
  • Price$560
  • Updated2021-12-16
  • Buy
  • ManufacturerJR MediChem
  • Product numberJR6-L3913
  • Product descriptionPyrrolidine,2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-,(2S)- 96%
  • Packaging1g
  • Price$398
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number095213
  • Product description(S)-2-(Bis(3,5-bis(trifluoromethyl)phenyl)-((trimethylsilyl)oxy)methyl)pyrrolidine 95%
  • Packaging1g
  • Price$1250
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number095213
  • Product description(S)-2-(Bis(3,5-bis(trifluoromethyl)phenyl)-((trimethylsilyl)oxy)methyl)pyrrolidine 95%
  • Packaging5g
  • Price$3960
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number677019
  • Product description(S)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol trimethylsilyl ether 97%
  • Packaging1g
  • Price$812
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number677019
  • Product description(S)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol trimethylsilyl ether 97%
  • Packaging5g
  • Price$1970
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Alichem 848821614 (S)-2-(Bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine 5g $610 2021-12-16 Buy
American Custom Chemicals Corporation ORS0001315 (S)-ALPHA,ALPHA-BIS[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-2-PYRROLIDINEMETHANOL TRIMETHYLSILYL ETHER 97.00% 1G $735.54 2021-12-16 Buy
American Custom Chemicals Corporation ORS0001315 (S)-ALPHA,ALPHA-BIS[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-2-PYRROLIDINEMETHANOL TRIMETHYLSILYL ETHER 97.00% 5G $1130.28 2021-12-16 Buy
Biosynth Carbosynth FB100522 (S)-2-[Bis[3,5-bis(trifluoromethyl)phenyl](trimethylsilyloxy)methyl]pyrrolidine 100mg $55 2021-12-16 Buy
Biosynth Carbosynth FB100522 (S)-2-[Bis[3,5-bis(trifluoromethyl)phenyl](trimethylsilyloxy)methyl]pyrrolidine 250mg $90 2021-12-16 Buy
Biosynth Carbosynth FB100522 (S)-2-[Bis[3,5-bis(trifluoromethyl)phenyl](trimethylsilyloxy)methyl]pyrrolidine 500mg $140 2021-12-16 Buy
Biosynth Carbosynth FB100522 (S)-2-[Bis[3,5-bis(trifluoromethyl)phenyl](trimethylsilyloxy)methyl]pyrrolidine 1g $220 2021-12-16 Buy
Biosynth Carbosynth FB100522 (S)-2-[Bis[3,5-bis(trifluoromethyl)phenyl](trimethylsilyloxy)methyl]pyrrolidine 2g $350 2021-12-16 Buy
Chemenu CM132747 (S)-2-(bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine 95% 5g $524 2021-12-16 Buy
Crysdot CD42000193 (S)-2-(Bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine 95+% 1g $203 2021-12-16 Buy
Crysdot CD42000193 (S)-2-(Bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine 95+% 5g $560 2021-12-16 Buy
JR MediChem JR6-L3913 Pyrrolidine,2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-,(2S)- 96% 1g $398 2021-12-16 Buy
Matrix Scientific 095213 (S)-2-(Bis(3,5-bis(trifluoromethyl)phenyl)-((trimethylsilyl)oxy)methyl)pyrrolidine 95% 1g $1250 2021-12-16 Buy
Matrix Scientific 095213 (S)-2-(Bis(3,5-bis(trifluoromethyl)phenyl)-((trimethylsilyl)oxy)methyl)pyrrolidine 95% 5g $3960 2021-12-16 Buy
Sigma-Aldrich 677019 (S)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol trimethylsilyl ether 97% 1g $812 2024-03-01 Buy
Sigma-Aldrich 677019 (S)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol trimethylsilyl ether 97% 5g $1970 2024-03-01 Buy

Properties

Melting point :48-56 °C
Boiling point :382.4±37.0 °C(Predicted)
Density :1.319±0.06 g/cm3(Predicted)
Flash point :110 °C
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly)
form :Solid
pka :9.34±0.10(Predicted)
color :White to Off-White

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(S)-α,α-Bis[3,5-di(trifluoromethyl)phenyl]-O-(trimethylsilyl)pyrrolidine-2-methanol, is a diarylprolinol silyl ether organocatalyst. It is able to catalyze a variety of bond-forming reactions such as C-C, C-N, C-O, C-S, and C-Hal in high yields and excellent levels of enantiocontrol.