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ChemicalBook >> CAS DataBase List >> 2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione

2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione

2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione price.
  • $5 - $6247.5
  • Product name: 2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione
  • CAS: 835616-60-9
  • MF: C13H9FN2O4
  • MW: 276.22
  • EINECS:
  • MDL Number:MFCD11840666
  • Synonyms:2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione;E3 ligase Ligand 4;1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fl...;Pomalidomide Related Compound 7;Thalidomide 4-fluoride;TC-E3 5032;E3 ligase Ligand 4(TC-E3 5032);1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fluoro-
37 prices
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  • Abosyn
  • Acrotein
  • AK Scientific
  • Ambeed
  • Biorbyt Ltd
  • Biosynth Carbosynth
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  • DC Chemicals
  • Tocris
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  • ManufacturerAbosyn
  • Product number10-3156
  • Product description2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione 95%-98%
  • Packaging1g
  • Price$1200
  • Updated2021-12-16
  • Buy
  • ManufacturerAcrotein
  • Product numberAS00641
  • Product description2-(2,6-Dioxo-piperidin-3-yl)-4-fluoroisoindoline-1,3-dione 97%
  • Packaging1g
  • Price$91.67
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number4916BB
  • Product description2-(2,6-Dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione
  • Packaging1g
  • Price$185
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number4916BB
  • Product description2-(2,6-Dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione
  • Packaging5g
  • Price$485
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number4916BB
  • Product description2-(2,6-Dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione
  • Packaging10g
  • Price$840
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA850967
  • Product description2-(2,6-Dioxo-piperidin-3-yl)-4-fluoroisoindoline-1,3-dione 98%
  • Packaging10mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA850967
  • Product description2-(2,6-Dioxo-piperidin-3-yl)-4-fluoroisoindoline-1,3-dione 98%
  • Packaging50mg
  • Price$6
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA850967
  • Product description2-(2,6-Dioxo-piperidin-3-yl)-4-fluoroisoindoline-1,3-dione 98%
  • Packaging100mg
  • Price$8
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA850967
  • Product description2-(2,6-Dioxo-piperidin-3-yl)-4-fluoroisoindoline-1,3-dione 98%
  • Packaging250mg
  • Price$11
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA850967
  • Product description2-(2,6-Dioxo-piperidin-3-yl)-4-fluoroisoindoline-1,3-dione 98%
  • Packaging1g
  • Price$38
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA850967
  • Product description2-(2,6-Dioxo-piperidin-3-yl)-4-fluoroisoindoline-1,3-dione 98%
  • Packaging5g
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA850967
  • Product description2-(2,6-Dioxo-piperidin-3-yl)-4-fluoroisoindoline-1,3-dione 98%
  • Packaging10g
  • Price$210
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA850967
  • Product description2-(2,6-Dioxo-piperidin-3-yl)-4-fluoroisoindoline-1,3-dione 98%
  • Packaging25g
  • Price$466
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA850967
  • Product description2-(2,6-Dioxo-piperidin-3-yl)-4-fluoroisoindoline-1,3-dione 98%
  • Packaging100g
  • Price$1390
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb611323
  • Product descriptionE3 ligase Ligand 4 >98%
  • Packaging1g
  • Price$1654.1
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611323
  • Product descriptionE3 ligase Ligand 4 >98%
  • Packaging5G
  • Price$4173.5
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Abosyn 10-3156 2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione 95%-98% 1g $1200 2021-12-16 Buy
Acrotein AS00641 2-(2,6-Dioxo-piperidin-3-yl)-4-fluoroisoindoline-1,3-dione 97% 1g $91.67 2021-12-16 Buy
AK Scientific 4916BB 2-(2,6-Dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione 1g $185 2021-12-16 Buy
AK Scientific 4916BB 2-(2,6-Dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione 5g $485 2021-12-16 Buy
AK Scientific 4916BB 2-(2,6-Dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione 10g $840 2021-12-16 Buy
Ambeed A850967 2-(2,6-Dioxo-piperidin-3-yl)-4-fluoroisoindoline-1,3-dione 98% 10mg $5 2021-12-16 Buy
Ambeed A850967 2-(2,6-Dioxo-piperidin-3-yl)-4-fluoroisoindoline-1,3-dione 98% 50mg $6 2021-12-16 Buy
Ambeed A850967 2-(2,6-Dioxo-piperidin-3-yl)-4-fluoroisoindoline-1,3-dione 98% 100mg $8 2021-12-16 Buy
Ambeed A850967 2-(2,6-Dioxo-piperidin-3-yl)-4-fluoroisoindoline-1,3-dione 98% 250mg $11 2021-12-16 Buy
Ambeed A850967 2-(2,6-Dioxo-piperidin-3-yl)-4-fluoroisoindoline-1,3-dione 98% 1g $38 2021-12-16 Buy
Ambeed A850967 2-(2,6-Dioxo-piperidin-3-yl)-4-fluoroisoindoline-1,3-dione 98% 5g $120 2021-12-16 Buy
Ambeed A850967 2-(2,6-Dioxo-piperidin-3-yl)-4-fluoroisoindoline-1,3-dione 98% 10g $210 2021-12-16 Buy
Ambeed A850967 2-(2,6-Dioxo-piperidin-3-yl)-4-fluoroisoindoline-1,3-dione 98% 25g $466 2021-12-16 Buy
Ambeed A850967 2-(2,6-Dioxo-piperidin-3-yl)-4-fluoroisoindoline-1,3-dione 98% 100g $1390 2021-12-16 Buy
Biorbyt Ltd orb611323 E3 ligase Ligand 4 >98% 1g $1654.1 2021-12-16 Buy
Biorbyt Ltd orb611323 E3 ligase Ligand 4 >98% 5G $4173.5 2021-12-16 Buy

Properties

Melting point :254-256°C
Boiling point :520.9±45.0 °C(Predicted)
Density :1.570±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Dichloromethane (Slightly, Heated), DMSO (Slightly)
pka :10.63±0.40(Predicted)
form :Solid
color :White to Off-White
InChI :InChI=1S/C13H9FN2O4/c14-7-3-1-2-6-10(7)13(20)16(12(6)19)8-4-5-9(17)15-11(8)18/h1-3,8H,4-5H2,(H,15,17,18)
InChIKey :CRAUTELYXAAAPW-UHFFFAOYSA-N
SMILES :C1(=O)C2=C(C(F)=CC=C2)C(=O)N1C1CCC(=O)NC1=O

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P281 Use personal protective equipment as required.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

4-Fluoro-thalidomide is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. It can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1 (HY-129966).