7-CHLORO-5-(2-CHLOROPHENYL)-1,5-DIHYDRO-4,1-BENZOTHIAZEPIN-2(3H)-ONE
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- $79 - $891
- Product name: 7-CHLORO-5-(2-CHLOROPHENYL)-1,5-DIHYDRO-4,1-BENZOTHIAZEPIN-2(3H)-ONE
- CAS: 75450-34-9
- MF: C15H11Cl2NOS
- MW: 324.22
- EINECS:
- MDL Number:MFCD09055422
- Synonyms:7-CHLORO-5-(2-CHLOROPHENYL)-1,5-DIHYDRO-4,1-BENZOTHIAZEPIN-2(3H)-ONE;CGP 37157;7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepine-2(3H)-one;4,1-Benzothiazepin-2(3H)-one, 7-chloro-5-(2-chlorophenyl)-1,5-dihydro-;7-chloro-5-(2-chlorophenyl)benzo[e][1,4]thiazepin-2(1H,3H,5H)-one;CGP-37157 - CAS 75450-34-9 - Calbiochem;1-benzothiazepine-2(3H)-one;7-Chloro-5-(2-chlorophenyl)-1
16 prices
Selected condition：
Brand
- AHH
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- ChemScene
- CSNpharm
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 5mg
- 10mg
- 25mg
- 0.05g
- 50mg
- 50
- 10
- 100mg
- ManufacturerAHH
- Product numberMT-04947
- Product description7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one 98%
- Packaging0.05g
- Price$502
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number0085BA
- Product description7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one
- Packaging10mg
- Price$259
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6602
- Product descriptionCGP-37157
- Packaging10mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6602
- Product descriptionCGP-37157
- Packaging50mg
- Price$757
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15611
- Product descriptionCGP 37157 ≥99%
- Packaging10mg
- Price$144
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15611
- Product descriptionCGP 37157 ≥99%
- Packaging50mg
- Price$682
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0008572
- Product descriptionCGP-37157 99.77%
- Packaging100mg
- Price$485
- Updated2021-12-16
- Buy
- ManufacturerCSNpharm
- Product numberCSN21135
- Product descriptionCGP-37157
- Packaging10mg
- Price$79
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberC8874
- Product descriptionCGP-37157 ≥98% (HPLC), powder
- Packaging5mg
- Price$159
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product number220005
- Product descriptionCGP-37157
- Packaging5mg
- Price$230
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberC8874
- Product descriptionCGP-37157 ≥98% (HPLC), powder
- Packaging25mg
- Price$630
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number1114
- Product descriptionCGP-37157 ≥99%(HPLC)
- Packaging10
- Price$212
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number1114
- Product descriptionCGP-37157 ≥99%(HPLC)
- Packaging50
- Price$891
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberC363745
- Product description7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one
- Packaging5mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberC363745
- Product description7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one
- Packaging25mg
- Price$525
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number254935
- Product descriptionCGP 37157
- Packaging10mg
- Price$466
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | MT-04947 | 7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one 98% | 0.05g | $502 | 2021-12-16 | Buy |
| AK Scientific | 0085BA | 7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one | 10mg | $259 | 2021-12-16 | Buy |
| ApexBio Technology | B6602 | CGP-37157 | 10mg | $160 | 2021-12-16 | Buy |
| ApexBio Technology | B6602 | CGP-37157 | 50mg | $757 | 2021-12-16 | Buy |
| Cayman Chemical | 15611 | CGP 37157 ≥99% | 10mg | $144 | 2024-03-01 | Buy |
| Cayman Chemical | 15611 | CGP 37157 ≥99% | 50mg | $682 | 2024-03-01 | Buy |
| ChemScene | CS-0008572 | CGP-37157 99.77% | 100mg | $485 | 2021-12-16 | Buy |
| CSNpharm | CSN21135 | CGP-37157 | 10mg | $79 | 2021-12-16 | Buy |
| Sigma-Aldrich | C8874 | CGP-37157 ≥98% (HPLC), powder | 5mg | $159 | 2024-03-01 | Buy |
| Sigma-Aldrich | 220005 | CGP-37157 | 5mg | $230 | 2024-03-01 | Buy |
| Sigma-Aldrich | C8874 | CGP-37157 ≥98% (HPLC), powder | 25mg | $630 | 2024-03-01 | Buy |
| Tocris | 1114 | CGP-37157 ≥99%(HPLC) | 10 | $212 | 2021-12-16 | Buy |
| Tocris | 1114 | CGP-37157 ≥99%(HPLC) | 50 | $891 | 2021-12-16 | Buy |
| TRC | C363745 | 7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one | 5mg | $140 | 2021-12-16 | Buy |
| TRC | C363745 | 7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one | 25mg | $525 | 2021-12-16 | Buy |
| Usbiological | 254935 | CGP 37157 | 10mg | $466 | 2021-12-16 | Buy |
Properties
Boiling point :479.8±45.0 °C(Predicted)
Density :1.384±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥20mg/mL
pka :12.20±0.40(Predicted)
form :White solid
color :white
Stability :Stable for 2 years from date of purchase as supplied. Solution in DMSO may be stored at -20°C for up to 3 months.
Density :1.384±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥20mg/mL
pka :12.20±0.40(Predicted)
form :White solid
color :white
Stability :Stable for 2 years from date of purchase as supplied. Solution in DMSO may be stored at -20°C for up to 3 months.
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Warning | |||||||||||||||||||||
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Description
CGP 37157 is a benzothiazepine that acts as a selective inhibitor of the mitochondrial sodium-calcium exchanger (IC50 = 0.36 μM in isolated mitochondria). It does not affect channels, exchangers, or ATPases on the cardiac sarcolemma or ATPases on sarcoplasmic reticulum. CGP 37157 is commonly used to study the role of mitochondrial-derived calcium in cytoplasmic calcium homeostasis. CGP 37157 inhibits sodium-dependent calcium efflux via the mitochondrial exchanger NCLX in a variety of cell types (IC50 = 5 μM).More related product prices
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