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ChemicalBook >> CAS DataBase List >> 2,4-Thiazolidinedione,5-(1,3-benzodioxol-5-ylmethylene)-

2,4-Thiazolidinedione,5-(1,3-benzodioxol-5-ylmethylene)-

2,4-Thiazolidinedione,5-(1,3-benzodioxol-5-ylmethylene)- price.
  • $72 - $483
  • Product name: 2,4-Thiazolidinedione,5-(1,3-benzodioxol-5-ylmethylene)-
  • CAS: 6318-41-8
  • MF: C11H7NO4S
  • MW: 249.24
  • EINECS:
  • MDL Number:MFCD18382117
  • Synonyms:2,4-Thiazolidinedione,5-(1,3-benzodioxol-5-ylmethylene)-;PI 3-Kγ Inhibitor VII - CAS 6318-41-8 - Calbiochem;Inhibitor,PI3Kγ,inhibit,Phosphoinositide 3-kinase,AS 041164,AS-041164,anti-inflammatory,neutrophil,recruitment,AS041164,RANTES,PI3K;5-(Benzo[d][1,3]dioxol-5-ylmethylene)thiazolidine-2,4-dione
14 prices
Selected condition：
Brand
  • aablocks
  • AK Scientific
  • Alfa Aesar
  • ApexBio Technology
  • Cayman Chemical
  • Sigma-Aldrich
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • Manufactureraablocks
  • Product numberAA000EXN
  • Product description2,4-Thiazolidinedione,5-(1,3-benzodioxol-5-ylmethylene)- ≥98%
  • Packaging5mg
  • Price$123
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA000EXN
  • Product description2,4-Thiazolidinedione,5-(1,3-benzodioxol-5-ylmethylene)- ≥98%
  • Packaging10mg
  • Price$143
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA000EXN
  • Product description2,4-Thiazolidinedione,5-(1,3-benzodioxol-5-ylmethylene)- ≥98%
  • Packaging50mg
  • Price$405
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1417AH
  • Product description5-((1,3-Benzodioxol-5-yl)methylene)-2,4-thiazolidinedione
  • Packaging50mg
  • Price$483
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67246
  • Product descriptionAS-041164 98%
  • Packaging10mg
  • Price$123
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4243
  • Product descriptionAS-041164
  • Packaging5mg
  • Price$81
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4243
  • Product descriptionAS-041164
  • Packaging10mg
  • Price$103
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4243
  • Product descriptionAS-041164
  • Packaging25mg
  • Price$233
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4243
  • Product descriptionAS-041164
  • Packaging50mg
  • Price$394
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13622
  • Product descriptionAS-041164
  • Packaging5mg
  • Price$72
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13622
  • Product descriptionAS-041164
  • Packaging10mg
  • Price$92
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13622
  • Product descriptionAS-041164
  • Packaging25mg
  • Price$207
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13622
  • Product descriptionAS-041164
  • Packaging50mg
  • Price$346
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number528114
  • Product descriptionPI 3-Kγ Inhibitor VII - CAS 6318-41-8 - Calbiochem
  • Packaging5mg
  • Price$238
  • Updated2023-01-07
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA000EXN 2,4-Thiazolidinedione,5-(1,3-benzodioxol-5-ylmethylene)- ≥98% 5mg $123 2021-12-16 Buy
aablocks AA000EXN 2,4-Thiazolidinedione,5-(1,3-benzodioxol-5-ylmethylene)- ≥98% 10mg $143 2021-12-16 Buy
aablocks AA000EXN 2,4-Thiazolidinedione,5-(1,3-benzodioxol-5-ylmethylene)- ≥98% 50mg $405 2021-12-16 Buy
AK Scientific 1417AH 5-((1,3-Benzodioxol-5-yl)methylene)-2,4-thiazolidinedione 50mg $483 2021-12-16 Buy
Alfa Aesar J67246 AS-041164 98% 10mg $123 2021-12-16 Buy
ApexBio Technology C4243 AS-041164 5mg $81 2021-12-16 Buy
ApexBio Technology C4243 AS-041164 10mg $103 2021-12-16 Buy
ApexBio Technology C4243 AS-041164 25mg $233 2021-12-16 Buy
ApexBio Technology C4243 AS-041164 50mg $394 2021-12-16 Buy
Cayman Chemical 13622 AS-041164 5mg $72 2024-03-01 Buy
Cayman Chemical 13622 AS-041164 10mg $92 2024-03-01 Buy
Cayman Chemical 13622 AS-041164 25mg $207 2024-03-01 Buy
Cayman Chemical 13622 AS-041164 50mg $346 2024-03-01 Buy
Sigma-Aldrich 528114 PI 3-Kγ Inhibitor VII - CAS 6318-41-8 - Calbiochem 5mg $238 2023-01-07 Buy

Properties

Density :1.595±0.06 g/cm3(Predicted)
storage temp. :+2C to +8C
solubility :Soluble in DMSO (up to 25 mg/ml).
form :Yellow solid
pka :7.13±0.20(Predicted)
color :Yellow
Stability : Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

The phosphatidylinositol 3-kinases (PI3Ks) are lipid and protein kinases involved in diverse biological processes, including cell growth, migration, and metabolism. AS-041164 is a potent inhibitor of PI3K with selectivity for the class IB isoform PI3Kγ (IC50 = 70 nM), compared to PI3Kα (IC50 = 240 nM), PI3Kβ (IC50 = 1.45 μM), and PI3Kδ (IC50 =1.70 μM). When tested at 1.0 μM, it shows little or no activity against 38 other common kinases. When given orally to mice, AS-041164 shows a pharmacokinetic profile that is similar to the general PI3K inhibitor LY294002 but is three times more potent (ED50 = 27.4 mg/kg for AS-041164 versus 81.6 mg/kg for LY294002) in blocking neutrophil recruitment induced by RANTES.

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